Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | APAF1 | O14727 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.60 |
| ▸ | FDPS | P14324 | 17/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL2395832 | 1.00 | MEN1 (0.60) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Bromide SCHEMBL2399324 | 1.00 | MEN1 (0.60) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Bromide SCHEMBL2396034 | 1.00 | MEN1 (0.60) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Bromide SCHEMBL2395677 | 1.00 | MEN1 (0.60) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Bromide SCHEMBL2395819 | 1.00 | MEN1 (0.60) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Bromide SCHEMBL2395867 | 1.00 | MEN1 (0.60) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL8450143 | 0.98 | MEN1 (0.57) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL16307692 | 0.98 | MEN1 (0.57) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL27921181 | 0.98 | MEN1 (0.57) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL31501079 | 0.98 | MEN1 (0.57) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109513039-B | Antibacterial hydrogel dressing containing imidazole bromide salt and preparation method and application thereof | 大连工业大学 | 2021-05-14 | — | — | CN | claimed |
| CN-111285951-A | Lipase/polyion liquid-styrene microsphere/hydrogel catalytic material and preparation method and application thereof | 大连工业大学 | 2020-06-16 | — | — | CN | claimed |
| CN-109513039-A | A kind of anti-bacterial hydrogel dressing of the bromide containing imidazoles and its preparation method and application | 大连工业大学 | 2019-03-26 | — | — | CN | claimed |
| CN-108579807-A | A kind of cross-linked polymeric acidic ion liquid alkylation catalyst and preparation method thereof | 江苏棋成化工有限公司 | 2018-09-28 | — | — | CN | claimed |
| CN-108097306-A | A kind of silica catalysis material of difunctionalization and its preparation and application | 中国科学院大连化学物理研究所 | 2018-06-01 | — | — | CN | claimed |
| CN-107141497-A | The preparation and its application of ionic organic porous films with solvent response | 国家纳米科学中心 | 2017-09-08 | — | — | CN | claimed |
| CN-114891167-A | Binary ionic liquid covalent bonding immobilized silicon-based material and preparation and application thereof | 武汉理工大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-114573750-A | Alkaline functionalized porous polyion liquid material as well as preparation method and application thereof | 浙江大学杭州国际科创中心 | 2022-06-03 | — | — | CN | disclosed |
| CN-113121743-B | Preparation method of self-repairing antibacterial hydrogel based on multiple interactions | 青岛科技大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-113150214-B | Preparation method of self-repairing antibacterial hydrogel containing imidazolium salt | 青岛科技大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-113174064-B | Preparation method of high-strength composite hydrogel | 青岛科技大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-113174064-A | Preparation method of high-strength composite hydrogel | 青岛科技大学 | 2021-07-27 | — | — | CN | disclosed |
| CN-113150214-A | Preparation method of self-repairing antibacterial hydrogel containing imidazolium salt | 青岛科技大学 | 2021-07-23 | — | — | CN | disclosed |
| US-20160114309-A1 | Polymeric Ionic Liquids, Methods of Making and Methods of Use Thereof | THE UNIVERSITY OF TOLEDO (US) | 2016-04-28 | — | — | US | disclosed |
| US-9249261-B2 | Polymeric ionic liquids, methods of making and methods of use thereof | THE UNIVERSITY OF TOLEDO (US) | 2016-02-02 | — | — | US | disclosed |
| US-8734673-B2 | Boron selective ionic liquids and polymeric ionic liquids, methods of making and methods of use thereof | THE UNIVERSITY OF TOLEDO (US) | 2014-05-27 | — | — | US | disclosed |
| US-20120111796-A1 | Boron Selective Ionic Liquids and Polymeric Ionic Liquids, Methods of Making and Methods of Use Thereof | UNIVERSITY OF TOLEDO (US) | 2012-05-10 | — | — | US | disclosed |
| US-20110236295-A1 | Polymeric Ionic Liquids, Methods of Making and Methods of Use Thereof | UNIVERSITY OF TOLEDO (US) | 2011-09-29 | — | — | US | disclosed |
| WO-2010017564-A1 | BORON SELECTIVE IONIC LIQUIDS AND POLYMERIC IONIC LIQUIDS, METHODS OF MAKING AND METHODS OF USE THEREOF | UNIVERSITY OF TOLEDO (US) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010017563-A1 | POLYMERIC IONIC LIQUIDS, METHODS OF MAKING AND METHODS OF USE THEREOF | UNIVERSITY OF TOLEDO (US) | 2010-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120111796-A1 | Boron Selective Ionic Liquids and Polymeric Ionic Liquids, Methods of Making and Methods of Use Thereof | BCCIP, SLC6A12, BOLA2; BOLA2B | MEN1 1196/4885HSP90AA1 4401/4885KMT2A 3451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.