Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELL | P14151 | 1/20 | 0.38 |
| ▸ | SELP | P16109 | 1/20 | 0.38 |
| ▸ | SELE | P16581 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SLC9A3 | P48764 | 2/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958599 | 0.77 | ERN1 (0.45) | ACHEERN1NOS2ALDH1A1MAPT | |
| SCHEMBL15449411 | 0.73 | SELL (0.58) | SELLSELPSELEACHEALDH1A1 | |
| SCHEMBL1185954 | 0.68 | ALDH1A1 (0.52) | SELLSELPSELEACHENOS2 | |
| Hydrochloric Acid SCHEMBL30811613 | 0.66 | ALDH1A1 (0.50) | SELLSELPSELEACHENOS2 | |
| Hydrochloric Acid SCHEMBL3121471 | 0.66 | ALDH1A1 (0.50) | SELLSELPSELEACHENOS2 | |
| SCHEMBL16257064 | 0.64 | SLC9A3 (0.47) | ALDH1A1MAPTGAAUSP2KDM4E | |
| SCHEMBL24041309 | 0.63 | SLC9A3 (0.46) | NOS2ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL18473810 | 0.63 | PDE10A (0.47) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL12957563 | 0.63 | MAPT (0.48) | ERN1ALDH1A1MAPTGAAMEN1 | |
| SCHEMBL20019478 | 0.62 | SLC9A3 (0.39) | ALDH1A1MAPTGAAKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |