Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.37 |
| ▸ | TUBB | P07437 | 2/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958620 | 0.77 | SELL (0.38) | ERN1ACHEALDH1A1MAPTGAA | |
| SCHEMBL23958596 | 0.76 | MAPT (0.44) | ERN1ALDH1A1SMN1; SMN2CYP3A4MAPT | |
| SCHEMBL5028318 | 0.74 | ACHE (0.59) | ERN1ACHEALDH1A1SMN1; SMN2CYP3A4 | |
| Hydrochloric Acid SCHEMBL8706033 | 0.72 | ACHE (0.56) | ERN1ACHEALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL27408145 | 0.70 | EP300 (0.48) | ERN1ACHEALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL4730926 | 0.69 | ALDH1A1 (0.56) | ERN1ACHEALDH1A1CYP3A4MAPT | |
| SCHEMBL30436671 | 0.69 | ACHE (0.52) | ERN1ACHEALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL11139031 | 0.69 | ACHE (0.52) | ERN1ACHEALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL13891035 | 0.67 | GRIN2D (0.54) | ERN1ALDH1A1CYP3A4MAPTNPSR1 | |
| SCHEMBL15906147 | 0.66 | MAPT (0.55) | ERN1ACHEALDH1A1SMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |