Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | BAD | Q92934 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23904827 | 0.83 | CES2 (0.38) | CES2CES1NOS3NOS1MAOA | |
| SCHEMBL23958937 | 0.82 | CES2 (0.37) | CES2CES1NOS3NOS1MAOA | |
| SCHEMBL23958880 | 0.80 | CES2 (0.45) | CES2CES1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL23904804 | 0.79 | MAOA (0.38) | CES2CES1NOS3NOS1MAOA | |
| SCHEMBL23959002 | 0.79 | CES2 (0.44) | CES2CES1NOS3NOS1 | |
| SCHEMBL17081962 | 0.69 | CES2 (0.50) | CES2CES1MAOAMAOBCA1 | |
| SCHEMBL208701 | 0.69 | CES2 (0.50) | CES2CES1MAOAMAOBCA1 | |
| SCHEMBL23837607 | 0.69 | SMN1; SMN2 (0.55) | CES2CES1NOS3NOS1LMNA | |
| SCHEMBL7937999 | 0.69 | SMN1; SMN2 (0.55) | CES2CES1NOS3NOS1LMNA | |
| SCHEMBL23905839 | 0.68 | MAPT (0.35) | CES2CES1NOS3NOS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |