Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MPL | P40238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958876 | 0.79 | CFTR (0.33) | AAK1 | |
| SCHEMBL23958867 | 0.78 | CFTR (0.32) | — | |
| SCHEMBL23958763 | 0.78 | CFTR (0.40) | AAK1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL23958626 | 0.78 | CFTR (0.40) | AAK1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL23958681 | 0.76 | CFTR (0.32) | AAK1 | |
| SCHEMBL23958688 | 0.76 | CFTR (0.32) | AAK1 | |
| SCHEMBL23958682 | 0.75 | XDH (0.34) | AAK1MEN1ALDH1A1KMT2A | |
| SCHEMBL23958714 | 0.71 | CFTR (0.40) | AAK1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL23958593 | 0.69 | CFTR (0.39) | AAK1 | |
| SCHEMBL4408689 | 0.61 | MAPT (0.45) | MEN1ALDH1A1LMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |