Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958596 | 0.85 | MAPT (0.44) | KDM4EPOLBL3MBTL1MAPTCA12 | |
| SCHEMBL23958829 | 0.82 | NOTUM (0.38) | KDM4EHTTPOLBL3MBTL1MAPT | |
| SCHEMBL23958621 | 0.81 | PDE4B (0.38) | HSD17B10 | |
| SCHEMBL23958630 | 0.78 | MAPT (0.40) | KDM4EHTTPOLBL3MBTL1MAPT | |
| SCHEMBL18033140 | 0.77 | POLB (0.41) | KDM4EHTTPOLBL3MBTL1NR1I2 | |
| SCHEMBL31160054 | 0.76 | MAPT (0.43) | KDM4EPOLBL3MBTL1NR1I2MAPT | |
| SCHEMBL18033225 | 0.74 | POLB (0.39) | KDM4EHTTPOLBL3MBTL1NR1I2 | |
| SCHEMBL18969560 | 0.74 | USP2 (0.46) | KDM4EPOLBL3MBTL1NR1I2MAPT | |
| SCHEMBL3988566 | 0.71 | MAPT (0.53) | KDM4EPOLBL3MBTL1NR1I2MAPT | |
| SCHEMBL18940642 | 0.70 | USP2 (0.43) | KDM4EPOLBL3MBTL1NR1I2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |