Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958822 | 0.85 | KDM4E (0.39) | MAPTKDM4EPOLBKMT2ALMNA | |
| SCHEMBL23958829 | 0.85 | NOTUM (0.38) | MAPTKDM4EPOLBKMT2ALMNA | |
| SCHEMBL23958621 | 0.84 | PDE4B (0.38) | HSD17B10 | |
| SCHEMBL23958630 | 0.83 | MAPT (0.40) | MAPTKDM4EPOLBKMT2ALMNA | |
| SCHEMBL10683847 | 0.81 | KDM4E (0.53) | MAPTKDM4EPOLBKMT2ALMNA | |
| SCHEMBL16545267 | 0.78 | KDM4E (0.40) | MAPTKDM4EPOLBKMT2ALMNA | |
| SCHEMBL23958599 | 0.76 | ERN1 (0.45) | MAPTNPSR1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL18031417 | 0.76 | KDM4E (0.53) | MAPTKDM4EPOLBKMT2ALMNA | |
| SCHEMBL30418756 | 0.76 | KDM4E (0.53) | MAPTKDM4EPOLBKMT2ALMNA | |
| SCHEMBL23905892 | 0.74 | CNR2 (0.49) | MAPTKDM4EPOLBKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |