Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23930187 | 0.78 | HRH4 (0.33) | HRH4SIGMAR1MAOAMAOB | |
| SCHEMBL22749877 | 0.78 | MAP3K14 (0.33) | POLBALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL1000205 | 0.78 | HRH4 (0.33) | HRH4SIGMAR1ALDH1A1CYP3A4MAOA | |
| SCHEMBL13508303 | 0.76 | POLB (0.35) | POLBALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL289511 | 0.76 | MAPT (0.50) | NQO2POLBALDH1A1TP53CYP3A4 | |
| SCHEMBL23958598 | 0.75 | HRH4 (0.33) | HRH4SIGMAR1 | |
| Bromide SCHEMBL15328872 | 0.75 | MAPT (0.48) | NQO2POLBALDH1A1TP53CYP3A4 | |
| SCHEMBL6119358 | 0.74 | MBOAT4 (0.33) | HRH4MBOAT4POLBALDH1A1TSHR | |
| SCHEMBL8572781 | 0.73 | ALPL (0.42) | HRH4ALDH1A1TDP1S1PR1MAOA | |
| SCHEMBL640891 | 0.73 | SCN5A (0.41) | HRH4POLBALDH1A1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |