Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 4/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25686954 | 0.90 | MAPT (0.36) | MAPTTDP1MMP13MMP1THRB | |
| SCHEMBL30211226 | 0.82 | MAPT (0.37) | MAPTTDP1MMP13MMP1THRB | |
| SCHEMBL23958824 | 0.82 | MAPT (0.37) | MAPTTDP1MMP13MMP1THRB | |
| SCHEMBL28909146 | 0.75 | MAPT (0.40) | MAPTTDP1MMP13MMP1THRB | |
| SCHEMBL26727263 | 0.75 | CFTR (0.33) | ALDH1A1 | |
| SCHEMBL23958823 | 0.74 | MMP13 (0.42) | MAPTTDP1MMP13MMP1THRB | |
| SCHEMBL25233350 | 0.73 | HTR2C (0.34) | MAPTPTGS2ALDH1A1 | |
| SCHEMBL26762177 | 0.73 | ALDH1A1 (0.33) | PTGS2ALDH1A1 | |
| SCHEMBL23958790 | 0.72 | CFTR (0.34) | ALDH1A1 | |
| SCHEMBL23958632 | 0.72 | CFTR (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |