Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958825 | 0.84 | SMN1; SMN2 (0.51) | NPC1CASP3RAB9ASMN1; SMN2SENP8 | |
| SCHEMBL7566122 | 0.84 | NPC1 (0.61) | NPC1CASP3RAB9ASMN1; SMN2SENP8 | |
| SCHEMBL30007207 | 0.78 | SLC6A4 (0.55) | NPC1CASP3RAB9ASMN1; SMN2SENP8 | |
| SCHEMBL23930092 | 0.78 | SLC6A4 (0.55) | NPC1CASP3RAB9ASMN1; SMN2SENP8 | |
| SCHEMBL26729108 | 0.77 | NPC1 (0.44) | NPC1CASP3RAB9ASMN1; SMN2SENP8 | |
| SCHEMBL23958828 | 0.76 | SMN1; SMN2 (0.52) | NPC1CASP3RAB9ASMN1; SMN2SENP8 | |
| SCHEMBL21349339 | 0.75 | KDM4E (0.47) | NPC1CASP3RAB9ASMN1; SMN2SENP8 | |
| SCHEMBL31752906 | 0.75 | KDM4E (0.47) | NPC1CASP3RAB9ASMN1; SMN2SENP8 | |
| SCHEMBL7562908 | 0.75 | NPC1 (0.57) | NPC1CASP3RAB9ASMN1; SMN2SENP8 | |
| SCHEMBL23930037 | 0.74 | SMN1; SMN2 (0.50) | NPC1CASP3RAB9ASMN1; SMN2SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |