Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | DHODH | Q02127 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958825 | 0.89 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9ACASP3SENP8 | |
| SCHEMBL30006707 | 0.88 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9ACASP3SENP8 | |
| SCHEMBL23930037 | 0.88 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9ACASP3SENP8 | |
| SCHEMBL25686480 | 0.85 | LMNA (0.49) | SMN1; SMN2NPC1RAB9ACASP3SENP8 | |
| SCHEMBL2513073 | 0.82 | NPC1 (0.56) | SMN1; SMN2NPC1RAB9ACASP3SENP8 | |
| SCHEMBL26791839 | 0.77 | ALDH1A1 (0.41) | SMN1; SMN2NPC1RAB9ACASP3SENP8 | |
| SCHEMBL23958849 | 0.76 | NPC1 (0.56) | SMN1; SMN2NPC1RAB9ACASP3SENP8 | |
| SCHEMBL18076802 | 0.75 | KDM4E (0.44) | SMN1; SMN2NPC1RAB9ACASP3SENP8 | |
| SCHEMBL30969925 | 0.75 | KDM4E (0.44) | SMN1; SMN2NPC1RAB9ACASP3SENP8 | |
| SCHEMBL2579354 | 0.75 | LMNA (0.49) | SMN1; SMN2NPC1RAB9ACASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |