SCHEMBL23958910

SCHEMBL23958910

CC1(C)c2ccccc2N(c2cc3c(cc2C#N)C(=O)c2cc(C#N)c(N4c5ccccc5C(C)(C)c5ccccc54)cc2-3)c2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP8 P40818 1/20 0.49
USP7 Q93009 1/20 0.49
PGR P06401 8/20 0.40
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
NPSR1 Q6W5P4 1/20 0.35
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
CRHBP P24387 1/20 0.33
HTT P42858 1/20 0.33
CRHR2 Q13324 1/20 0.33
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
MAPT P10636 1/20 0.33
GALR3 O60755 1/20 0.33
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
AR P10275 1/20 0.33
ALOX15 P16050 1/20 0.33
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20437401 0.86 PGR (0.38) PGRMEN1KMT2ANPSR1KDM4E
SCHEMBL20437396 0.86 PGR (0.38) USP8USP7PGRMEN1KMT2A
SCHEMBL20437392 0.81 PGR (0.39) PGRMEN1KMT2ANPSR1KDM4E
SCHEMBL23958884 0.81 PGR (0.44) USP8USP7PGR
SCHEMBL23959062 0.79 KMT2A (0.37) PGRMEN1KMT2ANPSR1KDM4E
SCHEMBL23958911 0.76 USP8 (0.33) USP8USP7
SCHEMBL19344985 0.76 PGR (0.43) PGRMEN1KMT2ANPSR1KDM4E
SCHEMBL19345045 0.76 PGR (0.43) PGRMEN1KMT2AKDM4EALDH1A1
SCHEMBL17954899 0.76 PGR (0.42) PGRMEN1KMT2AKDM4ECRHBP
SCHEMBL21426911 0.75 CYP1A2 (0.40) PGRMEN1KMT2ANPSR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11322694-B2 Electroluminescent material, method for manufacturing same, and light emitting device WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2022-05-03 US disclosed
US-20210336152-A1 ELECTROLUMINESCENT MATERIAL, METHOD FOR MANUFACTURING SAME, AND LIGHT EMITTING DEVICE WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2021-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11322694-B2 Electroluminescent material, method for manufacturing same, and light emitting device GPR17, CALCR, TAAR1 USP8 4588/4885USP7 3366/4885PGR 1412/4885
US-20210336152-A1 ELECTROLUMINESCENT MATERIAL, METHOD FOR MANUFACTURING SAME, AND LIGHT EMITTING DEVICE GPR17, CALCR, TAAR1 USP8 4588/4885USP7 3366/4885PGR 1412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.