SCHEMBL23958989

SCHEMBL23958989

CCc1ccccc1C1C(=O)N(C(=O)OC(C)(C)C)c2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.46
CACNB4 O00305 1/20 0.38
CACNA1A O00555 1/20 0.38
CACNA1G O43497 1/20 0.38
CACNG3 O60359 1/20 0.38
CACNA1F O60840 1/20 0.38
CACNA1H O95180 1/20 0.38
CACNB3 P54284 1/20 0.38
CACNA2D1 P54289 1/20 0.38
CACNG7 P62955 1/20 0.38
CACNA1B Q00975 1/20 0.38
CACNA1D Q01668 1/20 0.38
CACNB1 Q02641 1/20 0.38
CACNG1 Q06432 1/20 0.38
CACNB2 Q08289 1/20 0.38
CACNA1S Q13698 1/20 0.38
CACNA1C Q13936 1/20 0.38
CACNA1E Q15878 1/20 0.38
CACNA2D4 Q7Z3S7 1/20 0.38
CACNA2D3 Q8IZS8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23959036 0.86 BCHE (0.49) BCHECDK1KDM1ATSHRDTYMK
SCHEMBL18025768 0.83 BCHE (0.49) BCHECDK1KDM1AKLK7ABCB1
SCHEMBL23959084 0.82 BCHE (0.46) BCHECACNB4CACNA1ACACNA1GCACNG3
SCHEMBL23959040 0.82 BCHE (0.46) BCHECDK1KDM1ATSHRKLK7
SCHEMBL23959064 0.81 BCHE (0.44) BCHECDK1KDM1ALMNAL3MBTL1
SCHEMBL31499339 0.80 MEN1 (0.45) BCHECDK1KDM1A
SCHEMBL23959123 0.80 BCHE (0.43) BCHECDK1KDM1ATSHRLMNA
SCHEMBL31499320 0.79 BCHE (0.45) BCHECDK1KDM1ALMNA
SCHEMBL31274704 0.79 BCHE (0.52) BCHECDK1KDM1AKLK7ABCB1
SCHEMBL26628082 0.79 BCHE (0.52) BCHECDK1KDM1AKLK7ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021212974-A1 RACEMIC AND CHIRAL 3-(2,3-BUTADIENYL)OXYINDOLINONE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 复旦大学 (CN) 2021-10-28 WO disclosed