SCHEMBL23959040

SCHEMBL23959040

CPc1ccccc1C1C(=O)N(C(=O)OC(C)(C)C)c2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.46
CDK1 P06493 1/20 0.38
KDM1A O60341 1/20 0.37
GPR119 Q8TDV5 1/20 0.33
AADAT Q8N5Z0 1/20 0.33
DTYMK P23919 1/20 0.32
ABCB1 P08183 1/20 0.32
HDAC1 Q13547 2/20 0.31
HDAC6 Q9UBN7 2/20 0.31
DDB1 Q16531 1/20 0.31
CRBN Q96SW2 1/20 0.31
STS P08842 1/20 0.31
KLK7 P49862 1/20 0.31
TSHR P16473 1/20 0.31
TERT O14746 1/20 0.31
KDM4E B2RXH2 1/20 0.31
PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23959036 0.86 BCHE (0.49) BCHECDK1KDM1AGPR119AADAT
SCHEMBL18025768 0.83 BCHE (0.49) BCHECDK1KDM1AGPR119ABCB1
SCHEMBL23958989 0.82 BCHE (0.46) BCHECDK1KDM1AGPR119DTYMK
SCHEMBL23959084 0.82 BCHE (0.46) BCHECDK1KDM1AAADATKDM4E
SCHEMBL23959064 0.81 BCHE (0.44) BCHECDK1KDM1AGPR119KDM4E
SCHEMBL23959123 0.80 BCHE (0.43) BCHECDK1KDM1AGPR119TSHR
SCHEMBL31499320 0.79 BCHE (0.45) BCHECDK1KDM1AHDAC1PKM
SCHEMBL31274704 0.79 BCHE (0.52) BCHECDK1KDM1AGPR119AADAT
SCHEMBL26628082 0.79 BCHE (0.52) BCHECDK1KDM1AGPR119AADAT
SCHEMBL31499333 0.78 BCHE (0.44) BCHECDK1KDM1ASTSTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021212974-A1 RACEMIC AND CHIRAL 3-(2,3-BUTADIENYL)OXYINDOLINONE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 复旦大学 (CN) 2021-10-28 WO disclosed