SCHEMBL23959084

SCHEMBL23959084

COc1ccccc1C1C(=O)N(C(=O)OC(C)(C)C)c2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 2/20 0.46
P2RX3 P56373 1/20 0.41
HSD11B1 P28845 4/20 0.40
AADAT Q8N5Z0 1/20 0.40
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
GLA P06280 1/20 0.39
GAA P10253 1/20 0.39
HPGD P15428 1/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CACNB4 O00305 2/20 0.39
CACNA1A O00555 2/20 0.39
CACNA1G O43497 2/20 0.39
CACNG3 O60359 2/20 0.39
CACNA1F O60840 2/20 0.39
CACNA1H O95180 2/20 0.39
CACNB3 P54284 2/20 0.39
CACNA2D1 P54289 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23959036 0.86 BCHE (0.49) BCHEHSD11B1AADATALDH1A1GAA
SCHEMBL18025768 0.83 BCHE (0.49) BCHECDK1KDM1A
SCHEMBL31499333 0.83 BCHE (0.44) BCHEALDH1A1HPGDCDK1KDM1A
SCHEMBL23959040 0.82 BCHE (0.46) BCHEAADATKDM4ECDK1KDM1A
SCHEMBL23958989 0.82 BCHE (0.46) BCHECASP1CASP7CACNB4CACNA1A
SCHEMBL23959025 0.82 BCHE (0.41) BCHEAADATALDH1A1HPGDCDK1
SCHEMBL31499320 0.81 BCHE (0.45) BCHEALDH1A1CDK1KDM1A
SCHEMBL23959064 0.81 BCHE (0.44) BCHEKDM4EALDH1A1GAAHPGD
SCHEMBL31499326 0.80 ABCB1 (0.45) BCHEHSD11B1KDM4EALDH1A1GLA
SCHEMBL23959123 0.80 BCHE (0.43) BCHEGAACDK1KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021212974-A1 RACEMIC AND CHIRAL 3-(2,3-BUTADIENYL)OXYINDOLINONE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 复旦大学 (CN) 2021-10-28 WO disclosed