Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23959106 | 0.82 | PIM1 (0.38) | PIM1MAPTTP53POLBKMT2A | |
| SCHEMBL23959097 | 0.80 | PIM1 (0.36) | PIM1MAPTTP53POLBKMT2A | |
| SCHEMBL23959402 | 0.80 | PIM1 (0.36) | PIM1MAPTTP53POLBKMT2A | |
| SCHEMBL2242471 | 0.68 | MEN1 (0.45) | PIM1TP53KMT2AMEN1GAA | |
| SCHEMBL31079959 | 0.68 | MEN1 (0.45) | PIM1TP53KMT2AMEN1GAA | |
| SCHEMBL2499492 | 0.68 | BRD4 (0.57) | PIM1MAPTTP53POLBKMT2A | |
| SCHEMBL23959001 | 0.68 | MDM2 (0.43) | TP53ACHE | |
| SCHEMBL31220002 | 0.67 | MEN1 (0.44) | PIM1MAPTTP53KMT2AMEN1 | |
| SCHEMBL11829 | 0.67 | MEN1 (0.52) | PIM1TP53POLBKMT2AMEN1 | |
| SCHEMBL31440532 | 0.67 | MEN1 (0.52) | PIM1TP53POLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021212974-A1 | RACEMIC AND CHIRAL 3-(2,3-BUTADIENYL)OXYINDOLINONE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 复旦大学 (CN) | 2021-10-28 | — | — | WO | disclosed |