Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 4/20 | 0.32 |
| ▸ | MGAM | O43451 | 2/20 | 0.32 |
| ▸ | SI | P14410 | 2/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | SLC27A2 | O14975 | 1/20 | 0.32 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23959402 | 1.00 | PIM1 (0.36) | PIM1TP53MAPTPOLBKMT2A | |
| SCHEMBL23959106 | 0.87 | PIM1 (0.38) | PIM1TP53MAPTPOLBKMT2A | |
| SCHEMBL23959009 | 0.80 | PIM1 (0.39) | PIM1TP53MAPTPOLBKMT2A | |
| SCHEMBL23959001 | 0.73 | MDM2 (0.43) | TP53ACHE | |
| SCHEMBL23959029 | 0.71 | LMNA (0.47) | MAPTPOLBKMT2AMEN1GAA | |
| SCHEMBL23959081 | 0.70 | CASP1 (0.39) | TP53MAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL23959108 | 0.70 | CASP1 (0.39) | TP53MAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL1613300 | 0.65 | MEN1 (0.40) | PIM1TP53MAPTKMT2AMEN1 | |
| SCHEMBL2499492 | 0.64 | BRD4 (0.57) | PIM1TP53MAPTPOLBKMT2A | |
| SCHEMBL11829 | 0.63 | MEN1 (0.52) | PIM1TP53POLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021212974-A1 | RACEMIC AND CHIRAL 3-(2,3-BUTADIENYL)OXYINDOLINONE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 复旦大学 (CN) | 2021-10-28 | — | — | WO | disclosed |