SCHEMBL25757942

SCHEMBL25757942

CNC(C(=O)N1CCC[C@H]1C=O)C(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 7/20 0.39
STAT6 P42226 3/20 0.39
DPP8 Q6V1X1 4/20 0.38
DPP9 Q86TI2 4/20 0.38
FAP Q12884 3/20 0.38
DPP7 Q9UHL4 2/20 0.38
TUBB1 Q9H4B7 1/20 0.33
PITRM1 Q5JRX3 1/20 0.33
PREP P48147 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22525831 1.00 DPP4 (0.39) DPP4STAT6DPP8DPP9FAP
SCHEMBL8088388 0.87 DPP4 (0.40) DPP4STAT6DPP8DPP9FAP
SCHEMBL23959050 0.87 DPP4 (0.37) DPP4STAT6DPP8DPP9FAP
SCHEMBL21696763 0.86 STAT6 (0.43) DPP4STAT6DPP8DPP9FAP
SCHEMBL25885362 0.86 STAT6 (0.43) DPP4STAT6DPP8DPP9FAP
SCHEMBL26749977 0.85 DPP4 (0.35) DPP4STAT6DPP8DPP9FAP
SCHEMBL26749959 0.83 STAT6 (0.38) DPP4STAT6DPP8DPP9FAP
SCHEMBL26751293 0.83 STAT6 (0.36) DPP4STAT6DPP8DPP9FAP
SCHEMBL12811967 0.82 STAT6 (0.38) DPP4STAT6DPP8DPP9FAP
SCHEMBL8253773 0.81 ELANE (0.41) STAT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM UCHL3, UBE2L3, ADAM33 DPP4 1068/4885STAT6 4544/4885DPP8 831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.