Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 9/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28010843 | 0.82 | CTSK (0.58) | CTSKBRD4HSD11B1CYP2C9CA1 | |
| SCHEMBL3587515 | 0.82 | CTSK (0.58) | CTSKBRD4HSD11B1CYP2C9CA1 | |
| SCHEMBL29160932 | 0.79 | CTSK (0.58) | CTSKBRD4HSD11B1CYP2C9CA1 | |
| SCHEMBL12214163 | 0.79 | CTSK (0.58) | CTSKBRD4HSD11B1CYP2C9CA1 | |
| SCHEMBL1350948 | 0.79 | CTSK (0.58) | CTSKBRD4HSD11B1CYP2C9CA1 | |
| SCHEMBL29160931 | 0.79 | CTSK (0.58) | CTSKBRD4HSD11B1CYP2C9CA1 | |
| SCHEMBL1700228 | 0.79 | CTSK (0.58) | CTSKBRD4HSD11B1CYP2C9CA1 | |
| SCHEMBL4637428 | 0.78 | TSHR (0.55) | CTSKBRD4HSD11B1CYP2C9CA1 | |
| SCHEMBL25123847 | 0.76 | CTSK (0.54) | CTSKBRD4HSD11B1CYP2C9CA1 | |
| SCHEMBL30136791 | 0.75 | CA1 (0.57) | CTSKBRD4HSD11B1CYP2C9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214080-A1 | ANTIVIRAL 1,3-DI-OXO-INDENE COMPOUNDS | NOVARTIS AG (CH) | 2021-10-28 | — | — | WO | disclosed |