Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23959147 | 0.84 | KIF11 (0.41) | KIF11USP2ALDH1A1KDM4ETRPM8 | |
| Hydrochloric Acid SCHEMBL29776090 | 0.82 | KIF11 (0.40) | KIF11USP2ALDH1A1KDM4ETRPM8 | |
| SCHEMBL2304794 | 0.79 | KMT2A (0.41) | KIF11ALDH1A1NPC1KDM4EKMT2A | |
| SCHEMBL30194928 | 0.77 | HRH4 (0.38) | KIF11KMT2APIK3CD | |
| Hydrochloric Acid SCHEMBL27646829 | 0.77 | KMT2A (0.40) | KIF11ALDH1A1NPC1KDM4EKMT2A | |
| SCHEMBL30237770 | 0.71 | DPP4 (0.35) | KIF11NPC1RAB9AKMT2APIK3CD | |
| SCHEMBL299024 | 0.71 | — | — | |
| SCHEMBL5752803 | 0.71 | KMT2A (0.47) | KIF11ALDH1A1KMT2AMAPTPIK3CD | |
| SCHEMBL28210909 | 0.70 | PIK3CD (0.38) | KIF11ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL290564 | 0.70 | CDC7 (0.49) | ALDH1A1NPC1RAB9AKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214472-A1 | TETRAHYDROISOQUINOLINE COMPOUNDS AS NRF2 ACTIVATORS | C4X DISCOVERY LIMITED (GB) | 2021-10-28 | — | — | WO | disclosed |