SCHEMBL23959643

SCHEMBL23959643

CC(C)(C)c1cc(-c2cc(-c3cc(C(C)(C)C)cc(C(C)(C)C)c3)cc(-c3cc(-c4ccccc4)nc(-c4ccccc4)n3)c2)cc(C(C)(C)C)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 9/20 0.50
KMT2A Q03164 9/20 0.50
MAPT P10636 7/20 0.50
ALDH1A1 P00352 6/20 0.50
HPGD P15428 6/20 0.50
NTSR1 P30989 1/20 0.50
RXRA P19793 2/20 0.47
RXRB P28702 2/20 0.47
ADORA1 P30542 5/20 0.47
ADORA2A P29274 2/20 0.47
KDM4E B2RXH2 4/20 0.46
GAA P10253 1/20 0.46
NPSR1 Q6W5P4 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
CYP2C19 P33261 1/20 0.44
LMNA P02545 2/20 0.44
GLA P06280 1/20 0.44
RXRG P48443 1/20 0.44
TDP1 Q9NUW8 2/20 0.43
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23959746 0.95 MEN1 (0.53) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL23959649 0.95 MAPT (0.51) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL23959747 0.94 RXRA (0.56) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL23959641 0.92 RXRA (0.54) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL23959646 0.92 RXRA (0.54) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL23959744 0.92 RXRA (0.54) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL23959627 0.88 RXRB (0.53) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL23959657 0.88 RXRA (0.47) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL23928363 0.88 MAPT (0.55) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL23928336 0.88 MAPT (0.55) MEN1KMT2AMAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210336151-A1 Light-Emitting Device Material, Electron-Transport Layer Material, Organic Compound, Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2021-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210336151-A1 Light-Emitting Device Material, Electron-Transport Layer Material, Organic Compound, Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, and Lighting Device SPIN3, SLC39A3, SKIC3 MEN1 4132/4885KMT2A 3224/4885MAPT 1456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.