Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16449789 | 0.86 | ALDH1A1 (0.56) | HPGDALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL888841 | 0.86 | ALDH1A1 (0.56) | HPGDALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL25212796 | 0.84 | CYP1A2 (0.52) | HPGDALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL25212797 | 0.84 | CYP1A2 (0.52) | HPGDALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL23960349 | 0.83 | HPGD (0.47) | HPGDALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL25847074 | 0.83 | HPGD (0.47) | HPGDALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL12766240 | 0.83 | HPGD (0.47) | HPGDALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL12537187 | 0.82 | HPGD (0.46) | HPGDALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL19542979 | 0.81 | NPC1 (0.46) | HPGDALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL16449790 | 0.80 | PGR (0.47) | HPGDALDH1A1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021217019-A1 | RAS INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-10-28 | — | — | WO | disclosed |