Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23932334 | 0.83 | HRH1 (0.44) | SLC6A4HRH1KDM1AMAOAMAOB | |
| SCHEMBL23932349 | 0.79 | F10 (0.40) | SLC6A4HRH1OPRM1OPRK1KCNH2 | |
| SCHEMBL30151669 | 0.77 | BRD4 (0.41) | HRH1KDM1AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL11145850 | 0.76 | SLC6A4 (0.45) | SLC6A4HRH1SLC6A2SLC6A3HTR1A | |
| Hydrochloric Acid SCHEMBL11145855 | 0.76 | SLC6A4 (0.45) | SLC6A4HRH1SLC6A2SLC6A3HTR1A | |
| Hydrochloric Acid SCHEMBL11145846 | 0.76 | SLC6A4 (0.45) | SLC6A4HRH1SLC6A2SLC6A3HTR1A | |
| SCHEMBL23960572 | 0.74 | RORC (0.37) | OPRM1OPRK1KCNH2OPRD1 | |
| SCHEMBL23932369 | 0.74 | RORC (0.37) | OPRM1OPRK1KCNH2OPRD1 | |
| SCHEMBL12696888 | 0.73 | CSNK2A1 (0.45) | HRH1OPRM1OPRK1KCNH2MAOB | |
| SCHEMBL6290059 | 0.73 | HRH1 (0.59) | SLC6A4HRH1SLC6A2SLC6A3HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021216592-A1 | LOX ENZYME INHIBITING METHODS AND COMPOSITIONS | ANOVIA BIOSCIENCES, INC. (US) | 2021-10-28 | — | — | WO | disclosed |