SCHEMBL30151669

SCHEMBL30151669

CC(C)(C)OC(=O)NCc1cccc(OC2CNCC(c3ccccc3)C2)c1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 3/20 0.41
CREBBP Q92793 1/20 0.41
GLS O94925 3/20 0.40
HRH1 P35367 1/20 0.39
MAOA P21397 2/20 0.38
NAMPT P43490 1/20 0.38
ROCK2 O75116 1/20 0.37
CACNA1B Q00975 1/20 0.37
HDAC1 Q13547 1/20 0.37
KDM1A O60341 2/20 0.37
MAOB P27338 1/20 0.37
KDM4A O75164 1/20 0.37
JAK3 P52333 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26078682 1.00 BRD4 (0.41) BRD4CREBBPGLSHRH1MAOA
SCHEMBL23960541 0.89 NAMPT (0.44) MAOANAMPTHDAC1KDM1AMAOB
SCHEMBL23932334 0.88 HRH1 (0.44) HRH1MAOAKDM1AMAOBJAK3
SCHEMBL23960608 0.87 BRD4 (0.39) BRD4CREBBPGLSHRH1NAMPT
SCHEMBL30151671 0.87 BRD4 (0.39) BRD4CREBBPGLSHRH1NAMPT
SCHEMBL23960643 0.79 F2R (0.52) ROCK2
SCHEMBL30151697 0.79 F2R (0.52) ROCK2
SCHEMBL30636560 0.79 F2R (0.52) ROCK2
SCHEMBL23960647 0.77 SLC6A4 (0.43) HRH1MAOAKDM1AMAOB
SCHEMBL23932419 0.76 HSD17B10 (0.46) JAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230310445-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS ANOVIA BIOSCIENCES, INC. 2023-10-05 US disclosed
EP-4138824-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS Anovia Biosciences, Inc. (US) 2023-03-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230310445-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS LOX, LOXL1, LOXL2 BRD4 988/4885CREBBP 1574/4885GLS 499/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.