SCHEMBL23960839

SCHEMBL23960839

Cc1cc(C(C)(C)C)cc(C)c1-c1ccnc(Cl)c1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AAK1 Q2M2I8 2/20 0.40
IDO1 P14902 1/20 0.39
S1PR1 P21453 2/20 0.38
S1PR3 Q99500 1/20 0.38
PARP10 Q53GL7 1/20 0.37
PARP11 Q9NR21 1/20 0.37
KIF11 P52732 2/20 0.36
CCNC P24863 1/20 0.35
CDK8 P49336 1/20 0.35
SRC P12931 1/20 0.34
TGFBR1 P36897 1/20 0.34
POLB P06746 1/20 0.34
RECQL P46063 1/20 0.34
LOX P28300 1/20 0.34
LOXL3 P58215 1/20 0.34
LOXL2 Q9Y4K0 1/20 0.34
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34
MAPK14 Q16539 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17426507 0.84 IDO1 (0.42) AAK1IDO1S1PR1PARP10PARP11
SCHEMBL23960853 0.81 AAK1 (0.38) AAK1IDO1S1PR1S1PR3
SCHEMBL31337817 0.80 SRC (0.48) AAK1IDO1S1PR1PARP10PARP11
SCHEMBL23960856 0.80 PARP10 (0.44) AAK1IDO1S1PR1S1PR3PARP10
SCHEMBL23960912 0.80 ADORA2A (0.42) IDO1S1PR1S1PR3PARP10PARP11
SCHEMBL3281593 0.79 KIF11 (0.57) AAK1IDO1S1PR1S1PR3KIF11
SCHEMBL31380444 0.79 KIF11 (0.57) AAK1IDO1S1PR1S1PR3KIF11
SCHEMBL3361839 0.77 GRM5 (0.43) IDO1PARP10PARP11
SCHEMBL24140123 0.76 IDO1 (0.46) AAK1IDO1S1PR1S1PR3PARP10
SCHEMBL23960825 0.76 KIF11 (0.57) S1PR1S1PR3KIF11POLBRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210332290-A1 ORGANIC LIGHT-EMITTING MATERIAL BASED ON A PLATINUM TETRADENTATE ONCN COMPLEX, PREPARATION METHOD AND APPLICATION THEREOF IN ORGANIC LIGHT-EMITTING DIODES GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD (CN) 2021-10-28 US disclosed