SCHEMBL23960912

SCHEMBL23960912

CC(C)(C)c1cc(-c2ccccc2)c(-c2ccnc(Cl)c2)c(-c2ccccc2)c1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 2/20 0.42
ADORA1 P30542 1/20 0.42
TRPA1 O75762 1/20 0.37
KIF11 P52732 1/20 0.37
IDO1 P14902 2/20 0.36
PARP10 Q53GL7 1/20 0.36
PARP11 Q9NR21 1/20 0.36
MAPK14 Q16539 1/20 0.36
CYP19A1 P11511 1/20 0.35
RORC P51449 1/20 0.34
RORB Q92753 1/20 0.34
SHMT1 P34896 1/20 0.34
SHMT2 P34897 1/20 0.34
MAT2A P31153 1/20 0.34
S1PR1 P21453 1/20 0.34
S1PR3 Q99500 1/20 0.34
AKR1C3 P42330 1/20 0.34
AKR1C2 P52895 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23960860 0.80 KIF11 (0.54) KIF11MAPK14S1PR1S1PR3
SCHEMBL23960839 0.80 AAK1 (0.40) ADORA2AADORA1KIF11IDO1PARP10
SCHEMBL23960853 0.75 AAK1 (0.38) IDO1S1PR1S1PR3
SCHEMBL27333140 0.73 MAP4K4 (0.39) ADORA2AADORA1
SCHEMBL29461217 0.73 ADORA2A (0.56) ADORA2AADORA1TRPA1IDO1CYP19A1
SCHEMBL2329610 0.73 ADORA2A (0.56) ADORA2AADORA1TRPA1IDO1CYP19A1
SCHEMBL31380444 0.73 KIF11 (0.57) KIF11IDO1S1PR1S1PR3AKR1C2
SCHEMBL3281593 0.73 KIF11 (0.57) KIF11IDO1S1PR1S1PR3AKR1C2
SCHEMBL25070215 0.71 ADORA2A (0.54) ADORA2AADORA1TRPA1IDO1CYP19A1
SCHEMBL23960856 0.71 PARP10 (0.44) KIF11IDO1PARP10PARP11RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210332290-A1 ORGANIC LIGHT-EMITTING MATERIAL BASED ON A PLATINUM TETRADENTATE ONCN COMPLEX, PREPARATION METHOD AND APPLICATION THEREOF IN ORGANIC LIGHT-EMITTING DIODES GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD (CN) 2021-10-28 US disclosed