Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23960853 | 0.81 | AAK1 (0.38) | IDO1AAK1MKNK1BMP2K | |
| SCHEMBL31337817 | 0.77 | SRC (0.48) | IDO1ADORA2AADORA1TGFBR1MAPK14 | |
| SCHEMBL23960837 | 0.76 | KDM4E (0.35) | LMNAROCK2ROCK1IDO1ADORA2A | |
| SCHEMBL15672898 | 0.76 | ROCK2 (0.45) | ROCK2ROCK1IDO1ADORA2AADORA1 | |
| SCHEMBL30859075 | 0.74 | IKBKE (0.44) | LMNAFAAHCA1CA2CYP1A2 | |
| SCHEMBL25448967 | 0.74 | GABRA1 (0.45) | LMNAFAAHCA1CA2CYP1A2 | |
| SCHEMBL23058348 | 0.74 | GABRA1 (0.43) | LMNAROCK2ROCK1MAPK14FAAH | |
| SCHEMBL4903193 | 0.73 | ROCK2 (0.45) | ROCK2ROCK1IDO1TGFBR1MAPK14 | |
| SCHEMBL31380443 | 0.73 | ROCK2 (0.45) | ROCK2ROCK1IDO1TGFBR1MAPK14 | |
| SCHEMBL21363963 | 0.72 | KDM4C (0.35) | LMNATGFBR1FAAHCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210332290-A1 | ORGANIC LIGHT-EMITTING MATERIAL BASED ON A PLATINUM TETRADENTATE ONCN COMPLEX, PREPARATION METHOD AND APPLICATION THEREOF IN ORGANIC LIGHT-EMITTING DIODES | GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD (CN) | 2021-10-28 | — | — | US | disclosed |