Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.59 |
| ▸ | MAPT | P10636 | 8/20 | 0.59 |
| ▸ | NPC1 | O15118 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | GAA | P10253 | 5/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11876532 | 0.89 | ALDH1A1 (0.49) | ALDH1A1MAPTNPC1RAB9AMEN1 | |
| SCHEMBL333149 | 0.89 | ALDH1A1 (0.49) | ALDH1A1MAPTNPC1RAB9AMEN1 | |
| SCHEMBL11876526 | 0.89 | ALDH1A1 (0.49) | ALDH1A1MAPTNPC1RAB9AMEN1 | |
| SCHEMBL11882853 | 0.84 | MAPT (0.41) | ALDH1A1MAPTNPC1RAB9AMEN1 | |
| SCHEMBL11882848 | 0.84 | MAPT (0.41) | ALDH1A1MAPTNPC1RAB9AMEN1 | |
| SCHEMBL331733 | 0.84 | MAPT (0.41) | ALDH1A1MAPTNPC1RAB9AMEN1 | |
| SCHEMBL21436655 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MAPTNPC1RAB9AMEN1 | |
| SCHEMBL10053808 | 0.82 | MEN1 (0.41) | ALDH1A1MAPTNPC1RAB9AMEN1 | |
| SCHEMBL21436238 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MAPTNPC1RAB9AMEN1 | |
| SCHEMBL21055662 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MAPTNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210331122-A1 | TWO-DIMENSIONAL NANOPOROUS COVALENT ORGANIC FRAMEWORK FOR SELECTIVE SEPARATION AND FILTRATION MEMBRANE FORMED THEREFROM | UNIVERSITY OF WYOMING (US) | 2021-10-28 | — | — | US | disclosed |