SCHEMBL10053808

SCHEMBL10053808

O=C1C=Cc2ccccc2/C1=N/Nc1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
MAPT P10636 5/20 0.41
ALDH1A1 P00352 5/20 0.41
LMNA P02545 4/20 0.41
POLB P06746 3/20 0.41
PTPN1 P18031 2/20 0.41
HSD17B10 Q99714 2/20 0.41
KDM4E B2RXH2 1/20 0.41
BCHE P06276 1/20 0.41
PTPRC P08575 1/20 0.41
THRB P10828 1/20 0.41
PKM P14618 1/20 0.41
IDO1 P14902 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
ACHE P22303 1/20 0.41
CES1 P23141 1/20 0.41
RECQL P46063 1/20 0.41
PTPN22 Q9Y2R2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17460447 1.00 MEN1 (0.41) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL17460446 1.00 MEN1 (0.41) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL2858004 0.93 POLB (0.46) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL21436655 0.87 ALDH1A1 (0.41) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL15740338 0.87 EIF2AK2 (0.49) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL21436238 0.87 ALDH1A1 (0.41) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL21055662 0.87 ALDH1A1 (0.41) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL5344218 0.87 MEN1 (0.37) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL5344213 0.87 MEN1 (0.37) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL17762728 0.85 SNCA (0.41) MEN1KMT2AMAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3740185-B1 METHOD AND COMPOSITION FOR COLOURING AN EYEBROW COMPRISING AN ORGANIC ACID HSNF LTD (GB) 2023-09-20 EP disclosed
US-11648191-B2 Method and composition for colouring an eyebrow comprising an organic acid PERACHTM LIMITED (GB) 2023-05-16 US disclosed
US-11648191-B2 Method and composition for colouring an eyebrow comprising an organic acid PERACHTM LIMITED (GB) 2023-05-16 US disclosed
US-20200337968-A1 METHOD AND COMPOSITION FOR COLOURING AN EYEBROW COMPRISING AN ORGANIC ACID HSNF LIMITED (GB) 2020-10-29 US disclosed
WO-2019141959-A1 METHOD AND COMPOSITION FOR COLOURING AN EYEBROW COMPRISING AN ORGANIC ACID PERACHEM LIMITED (GB) 2019-07-25 WO disclosed
US-20170231889-A1 Sunscreen Compositions Comprising Colour Pigments BASF SE (DE) 2017-08-17 US disclosed
US-9364403-B2 Hair treatment methods PERACHEM LIMITED (GB) 2016-06-14 US disclosed
US-9364403-B2 Hair treatment methods PERACHEM LIMITED (GB) 2016-06-14 US disclosed
US-9320695-B2 Hair treatment methods PERACHEM LIMITED (GB) 2016-04-26 US disclosed
US-9320695-B2 Hair treatment methods PERACHEM LIMITED (GB) 2016-04-26 US disclosed
WO-2013150268-A2 HAIR TREATMENT METHODS PERACHEM LIMITED (GB) 2013-10-10 WO disclosed
WO-2013150269-A1 HAIR TREATMENT METHODS PERACHEM LIMITED (GB) 2013-10-10 WO disclosed
EP-2647408-A1 Hair treatment methods Perachem Limited (GB) 2013-10-09 EP disclosed
US-8268014-B2 Hair dyeing composition BASF SE Ludwigshafen (DE) 2012-09-18 US disclosed
US-8257448-B2 Hair dyeing composition BASF SE (DE) 2012-09-04 US disclosed
US-20120017931-A1 HAIR DYEING COMPOSITION BASF SE (DE) 2012-01-26 US disclosed
US-20120012128-A1 HAIR DYEING COMPOSITION BASF SE (DE) 2012-01-19 US disclosed
US-20110033400-A1 SUNSCREEN COMPOSITIONS COMPRISING COLOUR PIGMENTS BASF SE (US) 2011-02-10 US disclosed
US-20070251028-A1 Dyeing composition comprising at least one electrophilic monomer, one hydrophilic dye and one liquid organic solvent L'OREAL S.A. (FR) 2007-11-01 US disclosed
US-20070251028-A1 Dyeing composition comprising at least one electrophilic monomer, one hydrophilic dye and one liquid organic solvent L'OREAL S.A. (FR) 2007-11-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120012128-A1 HAIR DYEING COMPOSITION CYC1, CYB5R3, TYR MEN1 1913/4885KMT2A 2036/4885MAPT 4485/4885
US-20200337968-A1 METHOD AND COMPOSITION FOR COLOURING AN EYEBROW COMPRISING AN ORGANIC ACID CUTA, TYR, CYP2W1 MEN1 1887/4885KMT2A 3659/4885MAPT 1077/4885
US-20070251028-A1 Dyeing composition comprising at least one electrophilic monomer, one hydrophilic dye and one liquid organic solvent KRT18, DSG1, IK MEN1 4012/4885KMT2A 1545/4885MAPT 361/4885
US-11648191-B2 Method and composition for colouring an eyebrow comprising an organic acid CUTA, TYR, CYP2W1 MEN1 1887/4885KMT2A 3659/4885MAPT 1077/4885
US-20110033400-A1 SUNSCREEN COMPOSITIONS COMPRISING COLOUR PIGMENTS TYR, ERCC1, ERCC4 MEN1 1447/4885KMT2A 2807/4885MAPT 752/4885
US-20120017931-A1 HAIR DYEING COMPOSITION CYB5R3, CYC1, CYCS MEN1 2016/4885KMT2A 2264/4885MAPT 4571/4885
US-20170231889-A1 Sunscreen Compositions Comprising Colour Pigments TYR, ERCC1, ERCC4 MEN1 1447/4885KMT2A 2807/4885MAPT 752/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.