SCHEMBL23960924

SCHEMBL23960924

c1ccc(-c2ccccc2-c2cccc(-n3c4ccc5ccccc5c4c4c5ccccc5c5c(c6ccccc6n5-c5ccccc5)c43)c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
ATM Q13315 1/20 0.34
PDE10A Q9Y233 2/20 0.32
MAPK14 Q16539 1/20 0.32
MAPT P10636 3/20 0.31
ALDH1A1 P00352 2/20 0.31
HPGD P15428 1/20 0.31
KMT2A Q03164 4/20 0.31
IL1R1 P14778 1/20 0.31
MEN1 O00255 3/20 0.31
GAA P10253 1/20 0.31
HTT P42858 1/20 0.30
MCL1 Q07820 1/20 0.30
BAD Q92934 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
CDK4 P11802 2/20 0.30
CCND1 P24385 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23961003 0.92 L3MBTL1 (0.36) KDM4EL3MBTL1ATMMAPK14MAPT
SCHEMBL20865460 0.92 L3MBTL1 (0.36) KDM4EL3MBTL1ATMPDE10AMAPT
SCHEMBL22186533 0.92 L3MBTL1 (0.36) KDM4EL3MBTL1ATMPDE10AMAPT
SCHEMBL20865399 0.91 PDE10A (0.34) KDM4EL3MBTL1ATMPDE10AMAPT
SCHEMBL22187493 0.90 L3MBTL1 (0.35) KDM4EL3MBTL1ATMPDE10AMAPT
SCHEMBL22186770 0.90 L3MBTL1 (0.35) KDM4EL3MBTL1ATMPDE10AMAPT
SCHEMBL23960918 0.89 SIRT2 (0.33) L3MBTL1
SCHEMBL22186507 0.89 HSD17B1 (0.36) KDM4EL3MBTL1ATMPDE10AMAPT
SCHEMBL22186709 0.89 HSD17B1 (0.36) KDM4EL3MBTL1ATMPDE10AMAPT
SCHEMBL20865466 0.88 KDM4E (0.33) KDM4EL3MBTL1ATMMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210336153-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2021-10-28 US disclosed