Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 12/20 | 0.68 |
| ▸ | NR1H3 | Q13133 | 12/20 | 0.68 |
| ▸ | POLA1 | P09884 | 4/20 | 0.62 |
| ▸ | SOD1 | P00441 | 1/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26172616 | 1.00 | NR1H2 (0.68) | NR1H2NR1H3POLA1SOD1PTPN1 | |
| SCHEMBL29493613 | 1.00 | NR1H2 (0.68) | NR1H2NR1H3POLA1SOD1PTPN1 | |
| SCHEMBL29295288 | 1.00 | NR1H2 (0.68) | NR1H2NR1H3POLA1SOD1PTPN1 | |
| SCHEMBL6309781 | 0.93 | NR1H2 (0.69) | NR1H2NR1H3POLA1SOD1PTPN1 | |
| SCHEMBL6309780 | 0.93 | NR1H2 (0.69) | NR1H2NR1H3POLA1SOD1PTPN1 | |
| SCHEMBL6312187 | 0.91 | POLA1 (0.72) | NR1H2NR1H3POLA1PTPN1CYP2C9 | |
| SCHEMBL6312190 | 0.91 | POLA1 (0.72) | NR1H2NR1H3POLA1PTPN1CYP2C9 | |
| SCHEMBL20561120 | 0.91 | POLA1 (0.72) | NR1H2NR1H3POLA1PTPN1CYP2C9 | |
| SCHEMBL6309935 | 0.91 | POLA1 (0.72) | NR1H2NR1H3POLA1PTPN1CYP2C9 | |
| SCHEMBL6309929 | 0.91 | POLA1 (0.72) | NR1H2NR1H3POLA1PTPN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230035898-A1 | CYCLODEXTRIN PROTEIN DRUG CONJUGATES | REGENERON PHARMACEUTICALS, INC. | 2023-02-02 | — | — | US | disclosed |
| US-11377502-B2 | Anti-MSR1 antibodies and methods of use thereof | REGENERON PHARMACEUTICALS, INC. (US) | 2022-07-05 | — | — | US | disclosed |
| US-20220112158-A1 | BIS-OCTAHYDROPHENANTHRENE CARBOXAMIDES AND PROTEIN CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. | 2022-04-14 | — | — | US | disclosed |
| US-20210332080-A1 | HYDROPHILIC LINKERS FOR ANTIBODY DRUG CONJUGATES | REGENERON PHARMACEUTICALS, INC. | 2021-10-28 | — | — | US | disclosed |
| CN-113382985-A | Bis-octahydrophenanthrenecarboxamide derivatives and protein conjugates thereof as LXR agonists | 里珍纳龙药品有限公司 | 2021-09-10 | — | — | CN | disclosed |
| CN-112533951-A | anti-MSR 1 antibodies and methods of use thereof | 里珍纳龙药品有限公司 | 2021-03-19 | — | — | CN | disclosed |
| CN-111601619-A | Hydrophilic linkers for antibody drug conjugates | 里珍纳龙药品有限公司 | 2020-08-28 | — | — | CN | disclosed |
| CN-111065622-A | Bis-octahydrophenanthrenecarboxamides and protein conjugates thereof | 里珍纳龙药品有限公司 | 2020-04-24 | — | — | CN | disclosed |
| CN-110944718-A | Cyclodextrin protein drug conjugates | 里珍纳龙药品有限公司 | 2020-03-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210332080-A1 | HYDROPHILIC LINKERS FOR ANTIBODY DRUG CONJUGATES | CD44, CD47, EPCAM | NR1H2 3175/4885NR1H3 2873/4885POLA1 3401/4885 |
| US-20220112158-A1 | BIS-OCTAHYDROPHENANTHRENE CARBOXAMIDES AND PROTEIN CONJUGATES THEREOF | NR1H4, NR1H3, OGFR | NR1H2 4/4885NR1H3 2/4885POLA1 2752/4885 |
| US-20230035898-A1 | CYCLODEXTRIN PROTEIN DRUG CONJUGATES | SDCBP, DDOST, KRTCAP2 | NR1H2 1304/4885NR1H3 1332/4885POLA1 4011/4885 |
| US-11377502-B2 | Anti-MSR1 antibodies and methods of use thereof | CD47, MSR1, LDLR | NR1H2 195/4885NR1H3 128/4885POLA1 2693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.