Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 7/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 7/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 7/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 7/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 7/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 7/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | MGLL | Q99685 | 3/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | G6PD | P11413 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29140073 | 1.00 | PSEN1 (0.35) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL28709365 | 0.89 | PSEN1 (0.33) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL30208538 | 0.89 | PSEN1 (0.33) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL28579492 | 0.84 | TLR8 (0.35) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL13280166 | 0.84 | TLR8 (0.35) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8739988 | 0.78 | PKM (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL15274951 | 0.77 | PSEN1 (0.37) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL12184971 | 0.77 | PSEN1 (0.37) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9988363 | 0.77 | PSEN1 (0.37) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL20978319 | 0.77 | PSEN1 (0.37) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115947735-A | Organic small-molecule optical diagnosis and treatment reagent, nano-particles, preparation method and application thereof | 南京邮电大学 | 2023-04-11 | — | — | CN | claimed |
| CN-115947735-A | Organic small-molecule optical diagnosis and treatment reagent, nano-particles, preparation method and application thereof | 南京邮电大学 | 2023-04-11 | — | — | CN | disclosed |
| US-20180371157-A1 | THIADIAZOLOPYRIDINE POLYMERS, THEIR SYNTHESIS AND THEIR USE | MERCK PATENT GMBH (DE) | 2018-12-27 | — | — | US | disclosed |
| EP-3390496-A1 | THIADIAZOLOPYRIDINE POLYMERS, THEIR SYNTHESIS AND THEIR USE | Merck Patent GmbH (DE) | 2018-10-24 | — | — | EP | disclosed |
| WO-2017102058-A1 | THIADIAZOLOPYRIDINE POLYMERS, THEIR SYNTHESIS AND THEIR USE | MERCK PATENT GMBH (DE) | 2017-06-22 | — | — | WO | disclosed |
| EP-2550688-B1 | PYRROLO[3,2-B]PYRROLE SEMICONDUCTING COMPOUNDS AND DEVICES INCORPORATING SAME | RAYNERGY TEK INC (TW) | 2016-10-26 | — | — | EP | disclosed |
| US-8598448-B2 | Pyrrolo[3,2-B]pyrrole semiconducting compounds and devices incorporating same | POLYERA CORPORATION (US) | 2013-12-03 | — | — | US | disclosed |
| EP-2550688-A1 | PYRROLO[3,2-B]PYRROLE SEMICONDUCTING COMPOUNDS AND DEVICES INCORPORATING SAME | Polyera Corporation (US) | 2013-01-30 | — | — | EP | disclosed |
| WO-2011119446-A1 | PYRROLO[3,2-B]PYRROLE SEMICONDUCTING COMPOUNDS AND DEVICES INCORPORATING SAME | POLYERA CORPORATION (US) | 2011-09-29 | — | — | WO | disclosed |
| US-20110226338-A1 | PYRROLO[3,2-B]PYRROLE SEMICONDUCTING COMPOUNDS AND DEVICES INCORPORATING SAME | RAYNERGY TEK INC. (TW) | 2011-09-22 | — | — | US | disclosed |