SCHEMBL23964158

SCHEMBL23964158

c1ccc2[nH]c(CN3CCC(c4ccncc4)CC3)cc2c1

nearest known ligand 0.62

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 3/20 0.62
HRH4 Q9H3N8 1/20 0.56
SLC6A4 P31645 1/20 0.47
SLC6A3 Q01959 1/20 0.47
DRD2 P14416 6/20 0.46
DRD3 P35462 6/20 0.46
CCR8 P51685 1/20 0.46
HRH3 Q9Y5N1 1/20 0.45
KDM4E B2RXH2 1/20 0.45
ALDH1A1 P00352 1/20 0.45
DRD4 P21917 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5423444 0.90 CHRNA7 (0.76) CHRNA7HRH4SLC6A4SLC6A3DRD2
SCHEMBL5415378 0.84 CHRNA7 (0.59) CHRNA7HRH4SLC6A4SLC6A3DRD2
SCHEMBL30041061 0.83 HRH4 (0.54) CHRNA7HRH4SLC6A4SLC6A3DRD2
SCHEMBL23964187 0.83 HRH4 (0.54) CHRNA7HRH4SLC6A4SLC6A3DRD2
SCHEMBL28962396 0.81 DRD4 (0.64) CHRNA7HRH4SLC6A4SLC6A3DRD2
SCHEMBL30041451 0.80 HRH4 (0.63) HRH4DRD2DRD3HRH3DRD4
SCHEMBL23964200 0.80 HRH4 (0.63) HRH4DRD2DRD3HRH3DRD4
SCHEMBL5419290 0.78 CHRNA7 (0.57) CHRNA7HRH4SLC6A4SLC6A3DRD2
SCHEMBL31370749 0.78 DRD4 (0.69) CHRNA7DRD2KDM4EALDH1A1DRD4
SCHEMBL5427585 0.78 HRH4 (0.56) CHRNA7HRH4SLC6A4SLC6A3DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775261-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2025-04-08 CN disclosed
CN-115427404-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-12-13 CN disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
CN-115427404-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2022-12-02 CN disclosed
WO-2021216665-A9 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-12-02 WO disclosed
WO-2021216665-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF COL1A1, COL2A1, COL14A1 CHRNA7 4816/4885HRH4 4471/4885SLC6A4 4654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.