SCHEMBL23964160

SCHEMBL23964160

CCc1cncnc1N1CCN(Cc2cc3ccc(OCCOC)cc3[nH]2)CC1

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RPS6KB1 P23443 1/20 0.49
LRRK2 Q5S007 1/20 0.39
DRD2 P14416 10/20 0.38
DRD3 P35462 8/20 0.38
DRD4 P21917 4/20 0.38
PARP1 P09874 6/20 0.38
PARP2 Q9UGN5 4/20 0.37
KCNH2 Q12809 2/20 0.37
JAK2 O60674 1/20 0.37
JAK1 P23458 1/20 0.37
TYK2 P29597 1/20 0.37
JAK3 P52333 1/20 0.37
PDGFRB P09619 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30041144 1.00 RPS6KB1 (0.49) RPS6KB1LRRK2DRD2DRD3DRD4
SCHEMBL23964270 0.91 RPS6KB1 (0.51) RPS6KB1DRD2DRD3DRD4PARP1
SCHEMBL30041918 0.87 RPS6KB1 (0.47) RPS6KB1DRD2DRD3DRD4PARP1
SCHEMBL23932576 0.87 RPS6KB1 (0.47) RPS6KB1DRD2DRD3DRD4PARP1
SCHEMBL23932512 0.85 RPS6KB1 (0.68) RPS6KB1LRRK2DRD2DRD4PARP1
SCHEMBL30297617 0.83 RPS6KB1 (0.42) RPS6KB1DRD2DRD3DRD4PARP1
SCHEMBL23932483 0.83 RPS6KB1 (0.42) RPS6KB1DRD2DRD3DRD4PARP1
SCHEMBL23964268 0.83 RPS6KB1 (0.42) RPS6KB1DRD2DRD3DRD4PARP1
SCHEMBL23964271 0.83 RPS6KB1 (0.53) RPS6KB1DRD2DRD3DRD4PARP1
SCHEMBL30040691 0.83 RPS6KB1 (0.53) RPS6KB1DRD2DRD3DRD4PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
CN-115427404-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2022-12-02 CN disclosed
WO-2021216665-A9 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-12-02 WO disclosed
WO-2021216665-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF COL1A1, COL2A1, COL14A1 RPS6KB1 316/4885LRRK2 1529/4885DRD2 4780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.