Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 15/20 | 0.55 |
| ▸ | CTSL | P07711 | 12/20 | 0.55 |
| ▸ | CTSB | P07858 | 10/20 | 0.55 |
| ▸ | CTSK | P43235 | 6/20 | 0.55 |
| ▸ | PTGIR | P43119 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2396420 | 1.00 | CTSS (0.55) | CTSSCTSLCTSBCTSKPTGIR | |
| SCHEMBL3986964 | 0.88 | CTSS (0.67) | CTSSCTSLCTSBCTSK | |
| SCHEMBL3986961 | 0.88 | CTSS (0.67) | CTSSCTSLCTSBCTSK | |
| SCHEMBL13584665 | 0.88 | CTSS (0.67) | CTSSCTSLCTSBCTSK | |
| SCHEMBL2394907 | 0.85 | CTSS (0.58) | CTSSCTSLCTSBCTSK | |
| SCHEMBL2394902 | 0.85 | CTSS (0.58) | CTSSCTSLCTSBCTSK | |
| SCHEMBL2398486 | 0.83 | CTSS (0.82) | CTSSCTSLCTSBCTSK | |
| SCHEMBL12264344 | 0.83 | CTSS (0.69) | CTSSCTSLCTSBCTSK | |
| SCHEMBL2398489 | 0.83 | CTSS (0.82) | CTSSCTSLCTSBCTSK | |
| SCHEMBL2397033 | 0.80 | CTSS (0.74) | CTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8013186-B2 | Haloalkyl containing compounds as cysteine protease inhibitors | VIROBAY, INC. (US) | 2011-09-06 | — | — | US | disclosed |