Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 17/20 | 0.82 |
| ▸ | CTSL | P07711 | 15/20 | 0.82 |
| ▸ | CTSB | P07858 | 14/20 | 0.82 |
| ▸ | CTSK | P43235 | 10/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2398489 | 1.00 | CTSS (0.82) | CTSSCTSLCTSBCTSK | |
| SCHEMBL2442319 | 0.95 | CTSS (0.74) | CTSSCTSLCTSBCTSK | |
| SCHEMBL2442314 | 0.95 | CTSS (0.74) | CTSSCTSLCTSBCTSK | |
| SCHEMBL2397033 | 0.95 | CTSS (0.74) | CTSSCTSLCTSBCTSK | |
| SCHEMBL2398746 | 0.94 | CTSS (0.73) | CTSSCTSLCTSBCTSK | |
| SCHEMBL2398742 | 0.94 | CTSS (0.73) | CTSSCTSLCTSBCTSK | |
| SCHEMBL12264344 | 0.92 | CTSS (0.69) | CTSSCTSLCTSBCTSK | |
| SCHEMBL2399650 | 0.92 | CTSS (0.69) | CTSSCTSLCTSBCTSK | |
| SCHEMBL2399651 | 0.92 | CTSS (0.69) | CTSSCTSLCTSBCTSK | |
| SCHEMBL8266604 | 0.91 | CTSS (0.71) | CTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8013186-B2 | Haloalkyl containing compounds as cysteine protease inhibitors | VIROBAY, INC. (US) | 2011-09-06 | — | — | US | disclosed |
| US-20090023781-A1 | Haloalkyl Containing Compounds as Cysteine Protease Inhibitors | VIROBAY, INC. (US) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023781-A1 | Haloalkyl Containing Compounds as Cysteine Protease Inhibitors | CTSF, CTSS, CTSE | CTSS 2/4885CTSL 9/4885CTSB 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.