Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PPM1B | O75688 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22003027 | 0.75 | PPM1B (0.40) | CYP2C19PPM1BPTPN1PPP1CCSLC6A4 | |
| SCHEMBL18088607 | 0.75 | MEN1 (0.39) | CYP2C19PPM1BPTPN1PPP1CC | |
| SCHEMBL22003030 | 0.70 | KMT2A (0.39) | PPM1BPTPN1PPP1CC | |
| SCHEMBL19723953 | 0.66 | TBXA2R (0.34) | — | |
| SCHEMBL13715085 | 0.63 | CHRM2 (0.39) | PPM1BPTPN1PPP1CC | |
| SCHEMBL22826998 | 0.62 | PPM1B (0.40) | CYP2C19PPM1BPTPN1PPP1CCADRA2A | |
| SCHEMBL22806953 | 0.62 | PPM1B (0.40) | CYP2C19PPM1BPTPN1PPP1CCADRA2A | |
| SCHEMBL22806952 | 0.62 | PPM1B (0.40) | CYP2C19PPM1BPTPN1PPP1CCADRA2A | |
| SCHEMBL13246529 | 0.62 | PPM1B (0.40) | CYP2C19PPM1BPTPN1PPP1CCADRA2A | |
| SCHEMBL23963958 | 0.61 | CYP3A4 (0.35) | CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3901129-A1 | METHOD FOR SYNTHESISING NOVEL 3-HYDROXY-CYCLOPENTYL ACETIC ACID DERIVATIVE COMPOUNDS | L'OREAL (FR) | 2021-10-27 | — | — | EP | disclosed |