Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10716749 | 0.74 | TSHR (0.34) | HSD17B10TSHREPHX2BRD4 | |
| SCHEMBL10716754 | 0.74 | TSHR (0.34) | HSD17B10TSHREPHX2BRD4 | |
| SCHEMBL18088607 | 0.71 | MEN1 (0.39) | CYP2C9CYP2C19HSD17B10TSHREPHX2 | |
| SCHEMBL11746880 | 0.70 | MEN1 (0.32) | TSHRBRD4 | |
| SCHEMBL12810448 | 0.70 | BRD4 (0.32) | TSHRBRD4 | |
| SCHEMBL11742524 | 0.67 | TSHR (0.31) | TSHR | |
| SCHEMBL1863234 | 0.67 | — | — | |
| SCHEMBL8444550 | 0.67 | EPHX2 (0.44) | CYP2C19HSD17B10TSHREPHX2BRD4 | |
| SCHEMBL5638546 | 0.66 | TSHR (0.46) | CYP3A4MAPTCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL14499820 | 0.66 | TSHR (0.46) | CYP3A4MAPTCYP2C9CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3901129-A1 | METHOD FOR SYNTHESISING NOVEL 3-HYDROXY-CYCLOPENTYL ACETIC ACID DERIVATIVE COMPOUNDS | L'OREAL (FR) | 2021-10-27 | — | — | EP | disclosed |