Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PPM1B | O75688 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22003030 | 0.87 | KMT2A (0.39) | MEN1KMT2APPM1BPTPN1PPP1CC | |
| SCHEMBL22003027 | 0.86 | PPM1B (0.40) | MEN1KMT2APPM1BPTPN1PPP1CC | |
| SCHEMBL10716749 | 0.78 | TSHR (0.34) | BRD4TSHRHSD17B10MGAMGAA | |
| SCHEMBL10716754 | 0.78 | TSHR (0.34) | BRD4TSHRHSD17B10MGAMGAA | |
| SCHEMBL22003032 | 0.76 | PPM1B (0.41) | MEN1KMT2APPM1BPTPN1PPP1CC | |
| SCHEMBL22003031 | 0.76 | PPM1B (0.41) | MEN1KMT2APPM1BPTPN1PPP1CC | |
| SCHEMBL23964185 | 0.75 | CYP2C19 (0.35) | PPM1BPTPN1PPP1CCCYP2C19 | |
| SCHEMBL11746880 | 0.74 | MEN1 (0.32) | MEN1KMT2ABRD4TSHR | |
| SCHEMBL12810448 | 0.74 | BRD4 (0.32) | BRD4TSHR | |
| SCHEMBL23963958 | 0.71 | CYP3A4 (0.35) | CYP2C19BRD4TSHRCYP2C9HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3901129-A1 | METHOD FOR SYNTHESISING NOVEL 3-HYDROXY-CYCLOPENTYL ACETIC ACID DERIVATIVE COMPOUNDS | L'OREAL (FR) | 2021-10-27 | — | — | EP | disclosed |
| US-10995051-B2 | Method for synthesizing novel compounds derived from 3-hydroxy-cylopentyl acetic acid | L'OREAL (FR) | 2021-05-04 | — | — | US | disclosed |
| US-10654788-B2 | Method for synthesizing novel compounds derived from 3-hydroxy-cyclopentyl acetic acid | L'OREAL (FR) | 2020-05-19 | — | — | US | disclosed |
| US-20200131108-A1 | METHOD FOR SYNTHESIZING NOVEL COMPOUNDS DERIVED FROM 3-HYDROXY-CYLOPENTYL ACETIC ACID | L'OREAL (FR) | 2020-04-30 | — | — | US | disclosed |
| US-20180057440-A1 | METHOD FOR SYNTHESIZING NOVEL COMPOUNDS DERIVED FROM 3-HYDROXY-CYCLOPENTYL ACETIC ACID | L'OREAL (FR) | 2018-03-01 | — | — | US | disclosed |
| US-20180057440-A1 | METHOD FOR SYNTHESIZING NOVEL COMPOUNDS DERIVED FROM 3-HYDROXY-CYCLOPENTYL ACETIC ACID | L'OREAL (FR) | 2018-03-01 | — | — | US | disclosed |
| WO-2016146588-A1 | METHOD FOR SYNTHESIZING NOVEL COMPOUNDS DERIVED FROM 3-HYDROXY-CYCLOPENTYL ACETIC ACID | L'OREAL (FR) | 2016-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10654788-B2 | Method for synthesizing novel compounds derived from 3-hydroxy-cyclopentyl acetic acid | HSD17B12, FASN, AKR1C3 | MEN1 2623/4885KMT2A 2391/4885PPM1B 4097/4885 |
| US-20180057440-A1 | METHOD FOR SYNTHESIZING NOVEL COMPOUNDS DERIVED FROM 3-HYDROXY-CYCLOPENTYL ACETIC ACID | HSD17B12, FASN, AKR1C3 | MEN1 2623/4885KMT2A 2391/4885PPM1B 4097/4885 |
| US-10995051-B2 | Method for synthesizing novel compounds derived from 3-hydroxy-cylopentyl acetic acid | CYP8B1, HAAO, HSD17B12 | MEN1 1777/4885KMT2A 1629/4885PPM1B 2248/4885 |
| US-20200131108-A1 | METHOD FOR SYNTHESIZING NOVEL COMPOUNDS DERIVED FROM 3-HYDROXY-CYLOPENTYL ACETIC ACID | CYP8B1, HAAO, HSD17B12 | MEN1 1777/4885KMT2A 1629/4885PPM1B 2248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.