SCHEMBL23964225

SCHEMBL23964225

CCS(C)(C)c1cc(C)ccc1C

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.42
HTT P42858 2/20 0.42
ALDH1A1 P00352 5/20 0.42
TSHR P16473 2/20 0.42
GAA P10253 1/20 0.42
EDNRB P24530 2/20 0.41
EDNRA P25101 2/20 0.41
KMT2A Q03164 4/20 0.40
LMNA P02545 1/20 0.40
HPGD P15428 1/20 0.40
CYP2C19 P33261 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
KDM4E B2RXH2 1/20 0.39
F2 P00734 1/20 0.39
MAPT P10636 1/20 0.39
XBP1 P17861 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19416657 0.78 HTT (0.46) TDP1SMN1; SMN2HTTALDH1A1TSHR
SCHEMBL801935 0.77 ALDH1A1 (0.49) TDP1SMN1; SMN2HTTALDH1A1TSHR
SCHEMBL14212737 0.77 ALDH1A1 (0.44) TDP1SMN1; SMN2HTTALDH1A1TSHR
SCHEMBL7112755 0.75 UBE2N (0.57) TDP1SMN1; SMN2HTTALDH1A1TSHR
SCHEMBL25334167 0.74 ALDH1A1 (0.50) TDP1SMN1; SMN2HTTALDH1A1TSHR
SCHEMBL11775839 0.74 SMN1; SMN2 (0.43) TDP1SMN1; SMN2HTTALDH1A1TSHR
SCHEMBL801417 0.74 TDP1 (0.62) TDP1SMN1; SMN2HTTALDH1A1TSHR
SCHEMBL16712195 0.73 ALDH1A1 (0.49) TDP1SMN1; SMN2HTTALDH1A1TSHR
SCHEMBL10111130 0.73 ALDH1A1 (0.41) TDP1SMN1; SMN2HTTALDH1A1TSHR
SCHEMBL17319218 0.72 SMN1; SMN2 (0.60) TDP1SMN1; SMN2HTTALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021215838-A1 POLYSILOXANE-POLYCARBONATE COPOLYMER USING HYDROXY-TERMINATED POLYSILOXANE MIXTURE, AND METHOD FOR PRODUCING SAME 주식회사 삼양사 (KR) 2021-10-28 WO disclosed