SCHEMBL14212737

SCHEMBL14212737

Cc1ccc(C)c(S(C)(C)C)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.44
TDP1 Q9NUW8 3/20 0.44
TSHR P16473 2/20 0.43
GAA P10253 1/20 0.43
KMT2A Q03164 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
LMNA P02545 1/20 0.41
HPGD P15428 1/20 0.41
HTT P42858 3/20 0.40
KDM4E B2RXH2 1/20 0.40
F2 P00734 1/20 0.40
MAPT P10636 1/20 0.40
XBP1 P17861 1/20 0.40
CYP1A2 P05177 2/20 0.39
CYP2A6 P11509 2/20 0.39
TP53 P04637 1/20 0.39
EDNRB P24530 1/20 0.39
EDNRA P25101 1/20 0.39
UBE2N P61088 1/20 0.39
TAAR1 Q96RJ0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10111130 0.80 ALDH1A1 (0.41) ALDH1A1TDP1TSHRGAAKMT2A
SCHEMBL801935 0.80 ALDH1A1 (0.49) ALDH1A1TDP1TSHRGAAKMT2A
SCHEMBL13958296 0.79 TDP1 (0.44) ALDH1A1TDP1GAAKMT2ASMN1; SMN2
SCHEMBL7112755 0.77 UBE2N (0.57) ALDH1A1TDP1TSHRGAAKMT2A
SCHEMBL895530 0.77 ALDH1A1 (0.42) ALDH1A1TDP1TSHRGAAKMT2A
SCHEMBL25334167 0.77 ALDH1A1 (0.50) ALDH1A1TDP1TSHRGAAKMT2A
SCHEMBL23964225 0.77 TDP1 (0.44) ALDH1A1TDP1TSHRGAAKMT2A
SCHEMBL23084394 0.75 CYP3A4 (0.54) ALDH1A1TDP1TSHRKMT2ASMN1; SMN2
SCHEMBL16712195 0.75 ALDH1A1 (0.49) ALDH1A1TDP1TSHRGAAKMT2A
SCHEMBL246828 0.73 ALDH1A1 (0.51) ALDH1A1TDP1TSHRGAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230295381-A1 POLYSILOXANE-POLYCARBONATE COPOLYMER USING HYDROXY-TERMINATED POLYSILOXANE MIXTURE, AND METHOD FOR PRODUCING SAME SAMYANG CORPORATION (KR) 2023-09-21 US disclosed
US-20230295381-A1 POLYSILOXANE-POLYCARBONATE COPOLYMER USING HYDROXY-TERMINATED POLYSILOXANE MIXTURE, AND METHOD FOR PRODUCING SAME SAMYANG CORPORATION (KR) 2023-09-21 US disclosed
EP-4141046-A1 POLYSILOXANE-POLYCARBONATE COPOLYMER USING HYDROXY-TERMINATED POLYSILOXANE MIXTURE, AND METHOD FOR PRODUCING SAME Samyang Corporation (KR) 2023-03-01 EP disclosed
US-20220389174-A1 POLYCARBONATE COMPOSITE USING SOLID DISPERSION OR MOLTEN DISPERSION OF ANHYDROSUGAR ALCOHOL, PRODUCING METHOD THEREOF, AND MOLDED ARTICLE COMPRISING SAME SAMYANG CORPORATION (KR) 2022-12-08 US disclosed
WO-2021215838-A1 POLYSILOXANE-POLYCARBONATE COPOLYMER USING HYDROXY-TERMINATED POLYSILOXANE MIXTURE, AND METHOD FOR PRODUCING SAME 주식회사 삼양사 (KR) 2021-10-28 WO disclosed
WO-2021096213-A1 POLYCARBONATE COMPOSITE USING SOLID DISPERSION OR MOLTEN DISPERSION OF ANHYDROSUGAR ALCOHOL, PRODUCING METHOD THEREOF, AND MOLDED ARTICLE COMPRISING SAME 주식회사 삼양사 2021-05-20 WO disclosed
WO-2021086033-A1 POLYCARBONATE RESIN AND METHOD FOR PREPARING SAME 주식회사 삼양사 2021-05-06 WO disclosed
WO-2020060148-A1 POLYSILOXANE-POLYCARBONATE COPOLYMER HAVING HIGH IMPACT RESISTANCE, FLAME RESISTANCE AND TRANSPARENCY, AND PREPARATION METHOD THEREFOR 주식회사 삼양사 2020-03-26 WO disclosed
US-9951187-B2 Thermoplastic copolymer resin having excellent flame retardancy and transparency and preparation method therefor SAMYANG CORPORATION (KR) 2018-04-24 US disclosed
US-9951187-B2 Thermoplastic copolymer resin having excellent flame retardancy and transparency and preparation method therefor SAMYANG CORPORATION (KR) 2018-04-24 US disclosed
US-9062164-B2 Polysiloxane-polycarbonate copolymer and method of manufacturing the same SAMYANG CORPORATION (KR) 2015-06-23 US disclosed
US-9062164-B2 Polysiloxane-polycarbonate copolymer and method of manufacturing the same SAMYANG CORPORATION (KR) 2015-06-23 US disclosed
US-20140249280-A1 POLYSILOXANE-POLYCARBONATE COPOLYMER AND METHOD OF MANUFACTURING THE SAME SAMYANG CORPORATION (KR) 2014-09-04 US disclosed
US-8802804-B2 Hydroxy-terminated siloxane, polysiloxane-polycarbonate copolymer, and preparation method thereof SAMYANG CORPORATION (KR) 2014-08-12 US disclosed
US-8802804-B2 Hydroxy-terminated siloxane, polysiloxane-polycarbonate copolymer, and preparation method thereof SAMYANG CORPORATION (KR) 2014-08-12 US disclosed
WO-2013100494-A1 METHOD OF PREPARING POLYSILOXANE-POLYCARBONATE COPOLYMER SAMYANG CORPORATION (KR) 2013-07-04 WO disclosed
WO-2013066002-A1 POLYSILOXANE-POLYCARBONATE COPOLYMER AND METHOD OF MANUFACTURING THE SAME SAMYANG CORPORATION (KR) 2013-05-10 WO disclosed
WO-2013066000-A1 POLYCARBONATE RESIN COMPOSITION HAVING IMPROVED LOW-TEMPERATURE IMPACT RESISTANCE AND METHOD OF MANUFACTURING THE SAME SAMYANG CORPORATION (KR) 2013-05-10 WO disclosed
US-20120309922-A1 HYDROXY-TERMINATED SILOXANE, POLYSILOXANE-POLYCARBONATE COPOLYMER, AND PREPARATION METHOD THEREOF SAMYANG CORPORATION (KR) 2012-12-06 US disclosed
US-20120309922-A1 HYDROXY-TERMINATED SILOXANE, POLYSILOXANE-POLYCARBONATE COPOLYMER, AND PREPARATION METHOD THEREOF SAMYANG CORPORATION (KR) 2012-12-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120309922-A1 HYDROXY-TERMINATED SILOXANE, POLYSILOXANE-POLYCARBONATE COPOLYMER, AND PREPARATION METHOD THEREOF SEM1, P4HA1, SULT1A1 ALDH1A1 1059/4885TDP1 2378/4885TSHR 4298/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.