SCHEMBL23964294

SCHEMBL23964294

Cc1ncnc(N2CCNCC2)c1F

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 6/20 0.50
CYP1A2 P05177 3/20 0.44
CYP3A4 P08684 3/20 0.44
CYP2D6 P10635 2/20 0.44
MEN1 O00255 1/20 0.44
TSHR P16473 1/20 0.44
RECQL P46063 1/20 0.44
KMT2A Q03164 1/20 0.44
HTT P42858 1/20 0.43
ALDH1A1 P00352 2/20 0.42
CYP2C19 P33261 2/20 0.42
CLK4 Q9HAZ1 1/20 0.42
CHRNB2 P17787 1/20 0.41
CHRNA4 P43681 1/20 0.41
DRD2 P14416 1/20 0.40
LMNA P02545 1/20 0.40
KDM4E B2RXH2 1/20 0.40
MAPT P10636 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL23932474 0.98 HTR2C (0.49) HTR2CCYP1A2CYP3A4CYP2D6MEN1
SCHEMBL30040822 0.82 HTR2C (0.53) HTR2CCYP1A2CYP3A4CYP2D6MEN1
SCHEMBL9045898 0.82 HTR2C (0.53) HTR2CCYP1A2CYP3A4CYP2D6MEN1
Hydrochloric Acid SCHEMBL23932476 0.81 HTR2C (0.51) HTR2CCYP1A2CYP3A4CYP2D6MEN1
Hydrochloric Acid SCHEMBL30041876 0.81 HTR2C (0.51) HTR2CCYP1A2CYP3A4CYP2D6MEN1
SCHEMBL23964298 0.79 HTR2C (0.50) HTR2CCYP1A2CYP3A4CYP2D6MEN1
SCHEMBL31737420 0.79 HTR2C (0.50) HTR2CCYP1A2CYP3A4CYP2D6MEN1
SCHEMBL21442963 0.79 KDM4E (0.51) CYP1A2CYP3A4MEN1KMT2ACLK4
SCHEMBL23964360 0.79 HTR2C (0.50) HTR2CCYP1A2CYP3A4CYP2D6MEN1
Hydrochloric Acid SCHEMBL23932524 0.78 HTR2C (0.49) HTR2CCYP1A2CYP3A4CYP2D6MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
WO-2021216665-A9 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-12-02 WO disclosed
WO-2021216665-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF COL1A1, COL2A1, COL14A1 HTR2C 4659/4885CYP1A2 3367/4885CYP3A4 4190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.