Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | RCE1 | Q9Y256 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29404930 | 0.77 | PLAU (0.63) | ALDH1A1HSD17B10CYP3A4HPGDTSHR | |
| SCHEMBL29498391 | 0.77 | PLAU (0.63) | ALDH1A1HSD17B10CYP3A4HPGDTSHR | |
| SCHEMBL731002 | 0.77 | PLAU (0.63) | ALDH1A1HSD17B10CYP3A4HPGDTSHR | |
| SCHEMBL29351158 | 0.76 | ALDH1A1 (0.62) | ALDH1A1HSD17B10CYP3A4HPGDTSHR | |
| SCHEMBL5545202 | 0.76 | ALDH1A1 (0.62) | ALDH1A1HSD17B10CYP3A4HPGDTSHR | |
| SCHEMBL28780939 | 0.76 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CYP3A4HPGDTSHR | |
| SCHEMBL222833 | 0.74 | ALDH1A1 (0.54) | ALDH1A1HSD17B10CYP3A4HPGDTSHR | |
| SCHEMBL690212 | 0.74 | ALDH1A1 (0.54) | ALDH1A1HSD17B10CYP3A4HPGDTSHR | |
| SCHEMBL8006496 | 0.74 | ALDH1A1 (0.54) | ALDH1A1HSD17B10CYP3A4HPGDTSHR | |
| SCHEMBL4074869 | 0.74 | ALDH1A1 (0.54) | ALDH1A1HSD17B10CYP3A4HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021213518-A1 | COMPOUND FOR PREVENTING OR TREATING LIPID METABOLISM-RELATED DISEASES | 复旦大学 (CN) | 2021-10-28 | — | — | WO | disclosed |