Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 6/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL28432158 | 1.00 | KDM4E (0.52) | KDM4EALDH1A1TDP1CHRNA7CYP1A2 | |
| SCHEMBL81238 | 0.97 | KDM4E (0.54) | KDM4EALDH1A1TDP1CHRNA7CYP1A2 | |
| Hydrogen Sulfide SCHEMBL5998579 | 0.97 | KDM4E (0.54) | KDM4EALDH1A1TDP1CHRNA7CYP1A2 | |
| Benzene SCHEMBL29130108 | 0.97 | KDM4E (0.54) | KDM4EALDH1A1TDP1CHRNA7CYP1A2 | |
| Iodide SCHEMBL27389085 | 0.95 | KDM4E (0.48) | KDM4EALDH1A1TDP1CHRNA7CYP1A2 | |
| Water SCHEMBL1973851 | 0.95 | KDM4E (0.52) | KDM4EALDH1A1TDP1CHRNA7CYP1A2 | |
| Bromide SCHEMBL653934 | 0.95 | KDM4E (0.52) | KDM4EALDH1A1TDP1CHRNA7CYP1A2 | |
| Bromide SCHEMBL117943 | 0.95 | KDM4E (0.52) | KDM4EALDH1A1TDP1CHRNA7CYP1A2 | |
| SCHEMBL990633 | 0.95 | KDM4E (0.52) | KDM4EALDH1A1TDP1CHRNA7CYP1A2 | |
| Hydrochloric Acid SCHEMBL7263491 | 0.95 | KDM4E (0.58) | KDM4EALDH1A1TDP1CHRNA7CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 727 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4613751-A1 | METHOD OF MAKING CHEMICAL COMPOUNDS USEFUL FOR THE SYNTHESIS OF BUPRENORPHINE | Siegfried AG (CH) | 2025-09-10 | — | — | EP | claimed |
| CN-119529270-A | Tung oil-based non-isocyanate polyurethane soft foam and preparation method thereof | 中国林业科学研究院林产化学工业研究所 | 2025-02-28 | — | — | CN | claimed |
| CN-119264130-A | Preparation method of apixaban and intermediate thereof | 浙江华海药业股份有限公司 | 2025-01-07 | — | — | CN | claimed |
| CN-119118869-A | Recovery method of 2-cyano-2-valproic acid | 湖南省湘中制药有限公司 | 2024-12-13 | — | — | CN | claimed |
| CN-119081025-A | Strong-tensile hydrogel based on aromatic eutectic ionic liquid amphoteric lignin nano particles and preparation method thereof | 辽宁大学 | 2024-12-06 | — | — | CN | claimed |
| US-20240368063-A1 | PREPARATION METHOD, INTERMEDIATE COMPOUNDS, AND SYNTHESIS METHOD FOR A CLASS OF ANTHRACENE-DERIVED TOXINS IN ORGANIC CHEMISTRY | WUYAN PHARMACEUTICAL TECHNOLOGY (SHANGHAI) CO., LTD (CN) | 2024-11-07 | — | — | US | claimed |
| CN-115960343-B | High-activity oligomer catalyst and method for preparing alkylene oxide and cyclic anhydride alternating copolymer by using same | 大连理工大学 | 2024-04-02 | — | — | CN | claimed |
| CN-115650827-B | Preparation method, intermediate compound and synthesis method for anthracycline derivatives | 戊言医药科技（上海）有限公司 | 2024-03-15 | — | — | CN | claimed |
| CN-117285872-B | Hyperbranched epoxy graphene anticorrosive paint and preparation method and application thereof | 杭州本创科技有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-117285872-A | Hyperbranched epoxy graphene anticorrosive paint and preparation method and application thereof | 杭州本创科技有限公司 | 2023-12-26 | — | — | CN | claimed |
| US-20050043499-A1 | Ketone-aldehyde resins having low water content, high thermal stability and yellowing resistance | DEGUSSA AG (DE) | 2005-02-24 | — | — | US | claimed |
| US-20050010016-A1 | Resins based on ketones and aldehydes, having improved solubility properties and low color numbers | DEGUSSA AG (DE) | 2005-01-13 | — | — | US | claimed |
| US-6773822-B2 | ANTIFUNGAL AGENT MAY BE PRESENT IN THE GYPSUM CORE AND/OR ON ONE OR BOTH OF THE PAPER FACINGS, AND MAY BE ENCAPSULATED IN A MATERIAL THAT RELEASES THE ANTIFUNGAL AGENT OVER TIME AND/OR UPON EXPOSURE TO MOISTURE. | TEMPLE-INLAND FOREST PRODUCTS CORPORATION | 2004-08-10 | — | — | US | claimed |
| EP-0839862-B1 | Heat-aging-resistant polyamide resin composition and fiber comprising the same | MITSUBISHI GAS CHEMICAL CO (JP) | 2001-09-05 | — | — | EP | claimed |
| US-5929178-A | COMPRISING A COPPER COMPOUND, A HALIDE, AT LEAST ONE COMPOUND SELECTED FROM A HINDERED PHENOL AND A HINDERED AMINE, AN ORGANOPHOSPHORUS COMPOUND; EXCELLENT DURABILITY, TENSILE STRENGTH, HEAT-AGING-RESISTANCE UNDER HIGH-TEMPERATURE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1999-07-27 | — | — | US | claimed |
| EP-0839862-A1 | Heat-aging-resistant polyamide resin composition and fiber comprising the same | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1998-05-06 | — | — | EP | claimed |
| EP-0249125-B1 | PROCESS FOR THE PRODUCTION OF AN ELECTRICALLY CONDUCTIVE SURFACE LAYER ON MOULDED PLASTIC ARTICLES | BASF Aktiengesellschaft (DE) | 1991-10-16 | — | — | EP | claimed |
| US-4849531-A | Process for the preparation of 2,3-epoxyamides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-07-18 | — | — | US | claimed |
| US-4293702-A | FROM 2-ALKOXYBENZOTHIAZOLES; CATALYST OF TERTIARY AMINE, QUATERNARY AMMONIUM COMPOUND OR DIALKYL SULFATE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-10-06 | — | — | US | claimed |
| US-4012428-A | Method for preparing 3-methyl-2-(4-halogenophenyl)-butyronitrile | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-03-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240368063-A1 | PREPARATION METHOD, INTERMEDIATE COMPOUNDS, AND SYNTHESIS METHOD FOR A CLASS OF ANTHRACENE-DERIVED TOXINS IN ORGANIC CHEMISTRY | ANTXR2, AKR7A2, ACR | ACHE 306/4885KDM4E 3587/4885ALDH1A1 1295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.