Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 11/20 | 0.73 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.73 |
| ▸ | MAP1LC3B | Q9GZQ8 | 3/20 | 0.73 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.73 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.73 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.73 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.73 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.73 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.73 |
| ▸ | EGFR | P00533 | 1/20 | 0.73 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.73 |
| ▸ | ARAF | P10398 | 1/20 | 0.73 |
| ▸ | PIM1 | P11309 | 1/20 | 0.73 |
| ▸ | BRAF | P15056 | 1/20 | 0.73 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.73 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.73 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.73 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.73 |
| ▸ | MYOC | Q99972 | 1/20 | 0.73 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7742169 | 1.00 | RAF1 (0.73) | RAF1LRRK2MAP1LC3BPSEN1PSEN2 | |
| SCHEMBL5774039 | 0.86 | MAP1LC3B (0.88) | RAF1LRRK2MAP1LC3BPSEN1PSEN2 | |
| SCHEMBL5774043 | 0.86 | MAP1LC3B (0.88) | RAF1LRRK2MAP1LC3BPSEN1PSEN2 | |
| SCHEMBL3754416 | 0.86 | MAP1LC3B (0.88) | RAF1LRRK2MAP1LC3BPSEN1PSEN2 | |
| SCHEMBL19392080 | 0.85 | PLK4 (0.73) | RAF1LRRK2MAP1LC3BPSEN1PSEN2 | |
| SCHEMBL5771599 | 0.84 | RAF1 (0.73) | RAF1LRRK2MAP1LC3BPSEN1PSEN2 | |
| SCHEMBL7982725 | 0.84 | RAF1 (0.73) | RAF1LRRK2MAP1LC3BPSEN1PSEN2 | |
| SCHEMBL1395354 | 0.84 | LRRK2 (1.00) | RAF1LRRK2MAP1LC3BPSEN1PSEN2 | |
| Gw305074X SCHEMBL12199472 | 0.84 | RAF1 (1.00) | RAF1LRRK2MAP1LC3BPSEN1PSEN2 | |
| SCHEMBL3800644 | 0.84 | LRRK2 (1.00) | RAF1LRRK2MAP1LC3BPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4223770-A2 | NOVEL FUSION MOLECULES AND USES THEREOF | Foundation Medicine, Inc. (US) | 2023-08-09 | — | — | EP | disclosed |
| WO-2021213518-A1 | COMPOUND FOR PREVENTING OR TREATING LIPID METABOLISM-RELATED DISEASES | 复旦大学 (CN) | 2021-10-28 | — | — | WO | disclosed |