Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 3/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23974391 | 0.88 | PREP (0.32) | PREPPSMB5 | |
| SCHEMBL17721256 | 0.71 | LIPG (0.64) | LPLLIPGEGFR | |
| SCHEMBL18589064 | 0.69 | PREP (0.41) | PREPPSMB5EGFR | |
| SCHEMBL27026357 | 0.67 | PREP (0.39) | PREPPSMB5EGFR | |
| SCHEMBL13720661 | 0.67 | PREP (0.48) | PREPPSMB5 | |
| SCHEMBL12721154 | 0.67 | PREP (0.48) | PREPPSMB5 | |
| SCHEMBL13061975 | 0.65 | PREP (0.44) | PREPPSMB5 | |
| SCHEMBL30321063 | 0.65 | PREP (0.44) | PREPPSMB5 | |
| SCHEMBL12721140 | 0.62 | HRH3 (0.37) | PREPEGFR | |
| SCHEMBL23031440 | 0.62 | LIPG (0.62) | LPLLIPGEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210330798-A1 | TREATMENT OF INFECTIONS | ASCENDIS PHARMA A/S (DK) | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210330798-A1 | TREATMENT OF INFECTIONS | H1-10, PM20D2, ELANE | LPL 1424/4885LIPG 2384/4885PREP 555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.