Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23964455 | 0.88 | LPL (0.36) | PREPPSMB5 | |
| SCHEMBL21090587 | 0.68 | LPL (0.35) | — | |
| SCHEMBL14790147 | 0.67 | LPL (0.61) | — | |
| SCHEMBL13720661 | 0.66 | PREP (0.48) | PREPPSMB5 | |
| SCHEMBL12721154 | 0.66 | PREP (0.48) | PREPPSMB5 | |
| SCHEMBL21090361 | 0.63 | ESR1 (0.40) | — | |
| SCHEMBL18589064 | 0.62 | PREP (0.41) | PREPPSMB5 | |
| SCHEMBL24336324 | 0.62 | LIPG (0.57) | — | |
| SCHEMBL21090359 | 0.60 | ESR1 (0.42) | — | |
| SCHEMBL27026357 | 0.60 | PREP (0.39) | PREPPSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210338834-A1 | DEGRADABLE HYALURONIC ACID HYDROGELS | ASCENDIS PHARMA A/S (DK) | 2021-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210338834-A1 | DEGRADABLE HYALURONIC ACID HYDROGELS | CD44, HPSE, MMP13 | PREP 693/4885PSMB5 3501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.