Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CASR | P41180 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25761328 | 0.93 | CASR (0.49) | MAPTADRB2ADRB1ADRB3DNM1 | |
| SCHEMBL9165211 | 0.90 | S1PR2 (0.51) | ADRB2ADRB1ADRB3DNM1TSHR | |
| SCHEMBL12228656 | 0.89 | DNM1 (0.49) | ADRB2ADRB1ADRB3DNM1TSHR | |
| SCHEMBL9165276 | 0.88 | DNM1 (0.48) | ADRB2ADRB1ADRB3DNM1TSHR | |
| SCHEMBL17005472 | 0.85 | MAPT (0.60) | MAPTADRB2ADRB1ADRB3DNM1 | |
| SCHEMBL1327171 | 0.85 | MAPT (0.60) | MAPTADRB2ADRB1ADRB3DNM1 | |
| SCHEMBL2306548 | 0.85 | MAPT (0.60) | MAPTADRB2ADRB1ADRB3DNM1 | |
| SCHEMBL23386838 | 0.84 | KDM4E (0.50) | ADRB2ADRB1ADRB3DNM1TSHR | |
| SCHEMBL17005403 | 0.84 | CA1 (0.60) | ADRB2ADRB1ADRB3DNM1TSHR | |
| SCHEMBL24473808 | 0.84 | CA1 (0.60) | ADRB2ADRB1ADRB3DNM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3936226-A2 | CHROMATOGRAPHIC COLUMNS AND SEPARATION DEVICES COMPRISING A SUPERFICIALLY POROUS MATERIAL; AND USE THEREOF FOR SUPERCRITICAL FLUID CHROMATOGRAPHY AND OTHER CHROMATOGRAPHY | Waters Technologies Corporation (US) | 2022-01-12 | — | — | EP | disclosed |
| US-20210331138-A1 | CHROMATOGRAPHIC MATERIALS | WATERS TECHNOLOGIES CORPORATION (US) | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210331138-A1 | CHROMATOGRAPHIC MATERIALS | HAX1, CXCR1, YBX1 | MAPT 2565/4885ADRB2 1952/4885ADRB1 1231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.