SCHEMBL23964657

SCHEMBL23964657

Bc1ccc(C(C)(C)I)cc1

nearest known ligand 0.32

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
LMNA P02545 1/20 0.31
TYR P14679 1/20 0.31
ESR1 P03372 1/20 0.31
CYP3A4 P08684 1/20 0.31
AR P10275 1/20 0.31
HPGD P15428 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
HTR6 P50406 1/20 0.31
ESRRG P62508 1/20 0.31
SLC6A3 Q01959 1/20 0.31
ESR2 Q92731 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2868266 0.85 TSHR (0.40) TSHRLMNATYRESR1CYP3A4
SCHEMBL12640840 0.77 TSHR (0.55) TSHRLMNATYRHPGDHSD17B10
SCHEMBL13525 0.77 TSHR (0.55) TSHRLMNATYRHPGDHSD17B10
SCHEMBL24816539 0.77 KIF11 (0.44) TSHRLMNATYRESR1CYP3A4
SCHEMBL24816536 0.77 KIF11 (0.44) TSHRLMNATYRESR1CYP3A4
SCHEMBL15165483 0.77 ESR1 (0.52) TSHRLMNATYRESR1CYP3A4
SCHEMBL13227384 0.77 ESR1 (0.44) TSHRLMNATYRESR1CYP3A4
SCHEMBL8054363 0.74 APP (0.41) TSHRLMNATYRESR1CYP3A4
SCHEMBL14923048 0.74 TSHR (0.60) TSHRLMNA
SCHEMBL12101833 0.72 IDO1 (0.35) TSHRLMNATYRESR1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3681856-B1 COMPOUNDS HAVING PRESERVATIVE, ANTIMICROBIAL AND ANTISEPTIC ACTIVITY UNIV DEGLI STUDI MILANO (IT) 2021-10-27 EP disclosed