Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17121753 | 0.92 | KIF11 (0.56) | TSHRLMNATYRHDAC1KIF11 | |
| SCHEMBL12032170 | 0.92 | KIF11 (0.56) | TSHRLMNATYRHDAC1KIF11 | |
| SCHEMBL16595576 | 0.85 | TSHR (0.42) | TSHRLMNATYRHDAC1KIF11 | |
| SCHEMBL12163986 | 0.85 | CYP1A2 (0.53) | TSHRLMNATYRHDAC1ALDH1A1 | |
| SCHEMBL424728 | 0.83 | TSHR (0.73) | TSHRLMNATYRHDAC1KIF11 | |
| SCHEMBL12600290 | 0.82 | NPC1 (0.60) | TSHRLMNAHDAC1KIF11ALDH1A1 | |
| SCHEMBL15165483 | 0.81 | ESR1 (0.52) | TSHRLMNATYRHDAC1ALDH1A1 | |
| SCHEMBL13227384 | 0.81 | ESR1 (0.44) | TSHRLMNATYRHDAC1HPGD | |
| SCHEMBL29052426 | 0.80 | TSHR (0.32) | TSHRLMNATYR | |
| SCHEMBL24727658 | 0.80 | KIF11 (0.45) | TSHRLMNATYRHDAC1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199260-A2 | Boronic acid adducts of technetium-99M dioxime complexes | E.R. Squibb & Sons, Inc. (US) | 1986-10-29 | — | — | EP | claimed |
| US-12036219-B2 | Methods of treating infections in overweight and obese patients using antibiotics | MELINTA SUBSIDIARY CORP. (US) | 2024-07-16 | — | — | US | disclosed |
| EP-4289480-A2 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | F. Hoffmann-La Roche AG (CH) | 2023-12-13 | — | — | EP | disclosed |
| EP-4231064-A1 | COMPOSITIONS AND USE THEREOF IN PHOTOELECTRIC FIELD | Zhejiang Brilliant Optoelectronic Technology Co., Ltd. (CN) | 2023-08-23 | — | — | EP | disclosed |
| WO-2023095543-A1 | ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT | キヤノン株式会社 | 2023-06-01 | — | — | WO | disclosed |
| CN-112638961-B | Polyethylene compositions and films having superior properties | 诺瓦化学品(国际)股份有限公司 | 2023-03-28 | — | — | CN | disclosed |
| WO-2023016447-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-02-16 | — | — | WO | disclosed |
| WO-2023003234-A1 | COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF | 덕산네오룩스 주식회사 | 2023-01-26 | — | — | WO | disclosed |
| US-20220223795-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME | LT MATERIALS CO., LTD. (KR) | 2022-07-14 | — | — | US | disclosed |
| US-20220194939-A1 | Novel compounds and methods of use treating fructose-related disorders or diseases | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-06-23 | — | — | US | disclosed |
| US-20140191205-A1 | BIPOLAR COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE EMPLOYING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2014-07-10 | — | — | US | disclosed |
| WO-2014089904-A1 | TRIAZINONE COMPOUNDS | ABBVIE INC. (US) | 2014-06-19 | — | — | WO | disclosed |
| US-20140073624-A1 | Biaryl Heterocyclic Compounds and Methods of Making and Using the Same | RIB-X PHARMACEUTICALS, INC. (US) | 2014-03-13 | — | — | US | disclosed |
| WO-2012171609-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-12-20 | — | — | WO | disclosed |
| WO-2012091143-A1 | OPTICAL FILM, PROCESS FOR PRODUCING THE SAME, AND POLARIZING PLATE AND STEREOSCOPIC DISPLAY DEVICE AND SYSTEM HAVING THE SAME | FUJIFILM CORPORATION (JP) | 2012-07-05 | — | — | WO | disclosed |
| EP-2107047-B1 | Method for producing organic compounds by means of a transition metal-catalysed cross-coupling reaction of an aryl-X, heteroaryl-X, cycloalkenyl-X or alkenyl-X compound with an alkyl, alkenyl, cycloalkyl or cycloalkenyl halogenide | SALTIGO GMBH (DE) | 2011-09-28 | — | — | EP | disclosed |
| WO-2011044187-A1 | IMINOTHIADIAZINE DIOXIDE COMPOUNDS AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE | SCHERING CORPORATION (US) | 2011-04-14 | — | — | WO | disclosed |
| WO-2010127152-A2 | COMPOUNDS AND COMPOSITIONS AS MICROSOMAL PROSTAGLANDIN E SYNTHASE-1 INHIBITORS | IRM LLC (BM) | 2010-11-04 | — | — | WO | disclosed |
| US-20100264813-A1 | ORGANIC ELECTROLUMINESCENCE ELEMENT AND USE THEREOF | SHOWA DENKO K.K. (JP) | 2010-10-21 | — | — | US | disclosed |
| EP-2108690-A1 | Novel organic electroluminescent compounds and organic electroluminescent device using the same | Gracel Display Inc. (KR) | 2009-10-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12036219-B2 | Methods of treating infections in overweight and obese patients using antibiotics | NCEH1, NRDC, LPL | TSHR 3233/4885LMNA 2012/4885TYR 4242/4885 |
| US-20220223795-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME | CRY1, CYP1A1, CYP1B1 | TSHR 4090/4885LMNA 3994/4885TYR 48/4885 |
| US-20220194939-A1 | Novel compounds and methods of use treating fructose-related disorders or diseases | GCK, KHK, HK1 | TSHR 4224/4885LMNA 3355/4885TYR 3082/4885 |
| US-20140073624-A1 | Biaryl Heterocyclic Compounds and Methods of Making and Using the Same | PCNA, AADAC, MIF | TSHR 3560/4885LMNA 910/4885TYR 1195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.